Results 91 to 100 of about 613,864 (293)
Making WHO's work relevant to the Member States in SEA region. [PDF]
Lancet Reg Health Southeast Asia, 2023 Krishnan A.
europepmc +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Fifteen into one?: The European Union and its member states [PDF]
, 2003 Andreas Maurer, Jürgen Mittag
openalex +3 more sources
A REVISION OF THE TURONIAN MEMBERS OF THE AMMONITE SUBFAMILY COLLIGNONICERATINAE FROM THE UNITED STATES WESTERN INTERIOR AND GULF COAST [PDF]
, 2001 W. J. Kennedy +2 more
openalex +1 more source
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Regulatory authorities in the energy market of gas and electricity [PDF]
Zbornik Radova Pravnog Fakulteta u Splitu, 2015 In article is analysed the role of regulatory bodies on energetic market in European Union with special reference on situation in Croatia. In European Union existing common European market for electricity and gas. The market was in exclusive jurisdiction
Mirko Klarić
doaj
The Member States, the National Constitutions and the Scope of the Charter [PDF]
, 2001 L.F.M. Besselink
openalex +1 more source
European Business Law Review, 2017 The country-of-origin principle is frequently used as the foundation for secondary legislation aiming to realise the internal market. Even if it does promote free movement, the principle also has the consequence that host Member States to some extent lose the ability to regulate and supervise activities occurring in their territories.
openaire +4 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source