Results 41 to 50 of about 613,864 (293)

Secessions from EU Member States: The Imperative of Union's Neutrality

open access: yesEuropean Papers, 2016
(Series Information) European Papers - A Journal on Law and Integration, 2016 1(1), 67-92 | Article | (Table of Contents) I. Introduction. - II. A word about the artificiality of secessions' exceptionalism. - III.
Dimitry Kochenov, Martijn van den Brink
doaj   +1 more source

“Member States” and “Third States” in the Succession Regulation

open access: yesProblemy Prawa Prywatnego Międzynarodowego, 2020
The author advocates a flexible approach with respect to the interpretation of the term “Member State” as employed in the Succession Regulation, allowing the differentiation between “participating” and “non-participating” States. It does not mean that the term “Member State” should always be interpreted in a wide sense including the three non ...
openaire   +4 more sources

Member state liability in Europe and the United States [PDF]

open access: yesInternational Journal of Constitutional Law, 2006
The European Community (EC) and the United States have contrasting approaches to the place of member state liability to private parties as a remedy for the violation of the law of the union. The EC recognizes a general doctrine of member state liability in damages for violations of EC law, while American states generally possess sovereign immunity from
openaire   +3 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Tax reforms in EU member states [PDF]

open access: yesNewsletter - an occasional publication of the Institute of public finance, 2013
At a time of an exceptionally pronounced need for consolidation of Croatian public finance and discussions about changes in the Croatian taxation system, this paper analyses, on the basis of the European Commission reports1, tax changes that in 2011 and in the first half of 2012 EU Member States made to attempt to consolidate their public finances.
openaire   +2 more sources

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

ENVIRONMENTAL LIABILITY OF EU MEMBER STATES

open access: yesPravo, 2011
The framework for the system of Environmental Liability of EU Member States is primarly established by Directive 2004/35/CE of the European Parliament and of the Council on environmental liability with regard to the prevention and remedying of ...
Jelena Matijašević, Marijana Alavuk
doaj  

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

MEMBER STATES’ REGULATORY AUTONOMY IN HEALTH SERVICES WITHIN THE INTERNAL MARKET: THE IMPACT OF THE EUROPEAN LAW [PDF]

open access: yesEURINT, 2018
European Union (EU) law is based upon a liberalising imperative, the goal of which is to construct a single market between member states. Public healthcare is a fundamental task for the member states.
Olesea PLOTNIC, Elena CIOCHINA
doaj  

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