Results 91 to 100 of about 975,479 (295)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
The Multi-Criteria Negotiation Analysis Based on the Membership Function
Studies in Logic, Grammar and Rhetoric, 2014 In this paper we propose a multi-criteria model based on the fuzzy preferences approach which can be implemented in the prenegotiation phase to evaluate the negotiations packages.
Roszkowska Ewa, Wachowicz Tomasz
doaj +1 more source
Model-Based Method for Social Network Clustering
, 2018 We propose a simple mixed membership model for social network clustering in this note. A flexible function is adopted to measure affinities among a set of entities in a social network.
Dey, Dipak K. +2 more
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Fault Diagnosis for Complex Equipment Based on Belief Rule Base with Adaptive Nonlinear Membership Function. [PDF]
Entropy (Basel), 2023 Lian Z +5 more
europepmc +1 more source
Learning control of inverted pendulum system by neural network driven fuzzy reasoning: The learning function of NN-driven fuzzy reasoning under changes of reasoning environment [PDF]
Whereas conventional fuzzy reasonings are associated with tuning problems, which are lack of membership functions and inference rule designs, a neural network driven fuzzy reasoning (NDF) capable of determining membership functions by neural network is ...
Hayashi, Isao +2 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
ON DEFUZZIFICATION METHOD IN FUZZY EXPERT INFORMATION PROCESSING
Advanced Engineering Research, 2010 Some aspects of the defuzzification method in fuzzy expert information processing in the expert system for technological regulation of the machines are considered. An example of the method implementation is given in the article.
Valery P. DIMITROV +3 more
doaj