Results 111 to 120 of about 975,479 (295)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

OPTIMASI FUNGSI KEANGGOTAAN FUZZY MENGGUNAKAN METODE MAMDANI TERHADAP PREDIKSI PERILAKU PEMBELI

Techno.Com, 2015
Pengoptimalan penjualan dilakukan dengan berbagai cara, salah satunya dengan cara memprediksi perilaku pembeli. Dalam memprediksi perilaku pembeli logika fuzzy sangat baik digunakan dalam penelitian tersebut.
Sandhopi Sandhopi, Sendi Novianto, Erna Zuni Astuti   +2 more
doaj  

Agronomic evaluation of shade tolerance of 16 spring Camelina sativa (L.) Crantz genotypes under different artificial shade levels using a modified membership function. [PDF]

Front Plant Sci, 2022
Wang Y, Yu J, Gao Y, Li Z, Kim DS, Chen M, Fan Y, Zhang H, Yan X, Zhang CJ.   +9 more
europepmc   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Influence of machine learning membership functions and degree of membership function on each input parameter for simulation of reactors. [PDF]

Sci Rep, 2021
Pelalak R, Nakhjiri AT, Marjani A, Rezakazemi M, Shirazian S.   +4 more
europepmc   +1 more source

Analisis Perbandingan Single Membership Function dan Double Membership Function pada Diagnosis Penyakit ISPA

Jurnal Edukasi dan Penelitian Informatika (JEPIN)
Penyakit ISPA (Infeksi Saluran Pernafasan Akut) merupakan penyakit yang dapat menular. Penyakit ini disebabkan karena terjadinya infeksi dari bakteri maupun virus yang sering terjadi setiap tahunnya. Dalam keseharian, terkadang kita tidak dapat menyatakan sesuatu sebagai benar atau salah, namun kita harus menyatakannya dalam pernyataan hampir benar ...
Muhammad Fikri Hanif, Helen Sasty Pratiwi, Tursina Tursina   +2 more
openaire   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

MODIFIED S-CURVE MEMBERSHIP FUNCTION AND ITS APPLICATION TO FUZZY LINEAR PROGRAMMING

Journal of ICT, 2003
The modern trend in industrial application problem deserves modeling of all relevant vague or fuzzy information involved in a real decision making problem. In this paper, the modified S-curve membership function and its methodology in solving real life
Pandian M Vasant
doaj  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source