Results 51 to 60 of about 119,067 (262)

Functional Mixed Membership Models

Journal of Computational and Graphical Statistics
Mixed membership models, or partial membership models, are a flexible unsupervised learning method that allows each observation to belong to multiple clusters. In this paper, we propose a Bayesian mixed membership model for functional data. By using the multivariate Karhunen-Loève theorem, we are able to derive a scalable representation of Gaussian ...
Nicholas Marco, Damla Sentürk, Shafali Jeste, Charlotte DiStefano, Abigail Dickinson, Donatello Telesca   +5 more
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Membership Functions for Fuzzy Focal Elements [PDF]

Archives of Control Sciences, 2016
Abstract The paper presents a study on data-driven diagnostic rules, which are easy to interpret by human experts. To this end, the Dempster-Shafer theory extended for fuzzy focal elements is used. Premises of the rules (fuzzy focal elements) are provided by membership functions which shapes are changing according to input symptoms. The main aim of the
Porębski Sebastian, Straszecka Ewa
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Fuzzy Mandelbric Set and Its Perturbations by Dynamical Noises

Fractal and Fractional
In this paper, we introduce a membership function used to form the fuzzy Mandelbric set and investigate the structural effects of additive and multiplicative dynamic noises on it.
Nikola Popović, Soley Ersoy, İbrahim İnce, Ana Savić, Vladimir Baltić   +4 more
doaj   +1 more source

Type-II Fuzzy Decision Support System for Fertilizer

The Scientific World Journal, 2014
Type-II fuzzy sets are used to convey the uncertainties in the membership function of type-I fuzzy sets. Linguistic information in expert rules does not give any information about the geometry of the membership functions.
Ather Ashraf, Muhammad Akram, Mansoor Sarwar   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Genetic Algorithm-based Optimized Fuzzy Adaptive Path Selection in Wireless Sensor Networks

Sukkur IBA Journal of Computing and Mathematical Sciences, 2018
In Wireless sensor networks, energy efficiency can be achieved by adaptive choice of the data forwarding path to balance the energy dissipation in the network.
Muhammad Akram, Muhammad Ashraf, Tae Ho Cho   +2 more
doaj   +5 more sources

DECISION MAKING USING MODIFIED S-CURVE MEMBERSHIP FUNCTION IN FUZZY LINEAR PROGRAMMING PROBLEM

Journal of ICT, 2002
In order to develop approaches to solve a fuzzy linear programming problem, it is necessary to study first the formulation of membership functions and then the methodology for applying the solution to real life problems.
Pandian M. Vasant, R Nagarajan, Sazali Yaacob   +2 more
doaj