Results 101 to 110 of about 4,320,334 (318)
Faced with a pressing need for membranes with a higher permeability and selectivity, the field of membrane technology can benefit from a systematic framework for designing membranes with the necessary physical characteristics. In this work, we present an
Chang Liu +7 more
core +1 more source
In brain development, neural stem cells (NSCs) undergo asymmetric cell divisions to replicate themselves and meanwhile produce differentiating siblings. It remains obscure how NSCs preserve their self-renewing fate across mitosis.
Rulan Zhang +10 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Electro spinning is known as a simple and versatile method to produce nonwoven membranes made out of nanofibers. A wide range of polymers and blends can be used to yield nanofibers.
Gopal, R. +5 more
core +1 more source
RECYCLING OF SECONDARY RAW MILK WHEY DEMINERALIZATION AFTER THE TREATMENT BY REVERSE OSMOSIS
The possibility and the results of laboratory studies with the use of electrodialysis removing minerals from whey have been presented. The technical parameters of the electrodialysis installation (EDR-Z) have been calculated and displayed.
Arthur S. Merkel +3 more
doaj
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Silver Nanoparticle Impregnated Porous Carbon as a Nonenzymatic Hydrogen Peroxide Sensor
In this work, a non-enzymatic hydrogen peroxide sensor has successfully been realized based on Ag nanoparticles doped carbon modified carbon paste electrode (AgNPs/C-CPE) in pH = 7 phosphate buffer solution (PBS).
Yi-Song Zou +5 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source

