Results 151 to 160 of about 6,904,879 (418)
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Molecular Oncology, EarlyView.We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock +10 more
wiley +1 more source
Membrane-mediated interactions between arc-shaped particles strongly depend on membrane curvature [PDF]
arXivBesides direct molecular interactions, proteins and nanoparticles embedded in or adsorbed to membranes experience indirect interactions that are mediated by the membranes. These membrane-mediated interactions arise from the membrane curvature induced by the particles and can lead to assemblies of particles that generate highly curved spherical or ...
arxiv
Membrane boundary condition [PDF]
arXiv, 2000 Using a microscopic phase-space model of the membrane system, the boundary condition at a membrane is derived. According to the condition, the substance flow across the membrane is proportional to the difference of the substance concentrations at the opposite membrane surfaces.
arxiv
Quantum measurement backaction from a BEC coupled to a mechanical oscillator
, 2011 We study theoretically the dynamics of a a hybrid optomechanical system consisting of a macroscopic mechanical membrane magnetically coupled to a spinor Bose-Einstein condensate via a nanomagnet attached at the membrane center.
K. C. Schwab +6 more
core +1 more source
Molecular Oncology, EarlyView.CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar +4 more
wiley +1 more source
MEMBRANE EQUILIBRIA AND THE ELECTRIC CHARGE OF RED BLOOD CELLS [PDF]
, 1924 Calvin B. Coulter
openalex +1 more source
Statistical Mechanics of Membrane Protein Conformation: A Homopolymer Model
, 1998 The conformation and the phase diagram of a membrane protein are investigated via grand canonical ensemble approach using a homopolymer model. We discuss the nature and pathway of $\alpha$-helix integration into the membrane that results depending upon ...
A. Baumgärtner +29 more
core +2 more sources
Membrane proteins and membrane structure [PDF]
FEBS Letters, 1972 David E. Green, Roderick A. Capaldi
openaire +3 more sources
Molecular Oncology, EarlyView.Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy +12 more
wiley +1 more source
Calculable membrane theory [PDF]
arXiv, 2009 The key to membrane theory is to enlarge the diffeomorphism group until 4D gravity becomes almost topological. Just one ghost survives and its central charges can cancel against matter. A simple bosonic membrane emerges, but its flat D = 28 target space is unstable.
arxiv