Results 151 to 160 of about 8,110,093 (383)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Molecular Basis of Bacterial Outer Membrane Permeability Revisited

Microbiology and Molecular Biology Reviews, 2003
H. Nikaido
semanticscholar   +1 more source

Membrane fluidity and membrane fusion [PDF]

Biochemical Journal, 1972
J I, Howell, Q F, Ahkong, F C, Cramp, D, Fisher, W, Tampion, J A, Lucy   +5 more
openaire   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Multiplexed representation of others in the hippocampal CA1 subfield of female mice

Nature Communications
Hippocampal place cells represent the position of a rodent within an environment. In addition, recent experiments show that the CA1 subfield of a passive observer also represents the position of a conspecific performing a spatial task.
Xiang Zhang, Qichen Cao, Kai Gao, Cong Chen, Sihui Cheng, Ang Li, Yuqian Zhou, Ruojin Liu, Jun Hao, Emilio Kropff, Chenglin Miao   +10 more
doaj   +1 more source

Structure of membrane tethers and their role in fusion [PDF]

, 2019
Christian Ungermann, Daniel Kümmel
openalex   +1 more source

Membrane lipids: where they are and how they behave

Nature reviews. Molecular cell biology, 2008
G. Meer, D. Voelker, G. Feigenson
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Topological quantum materials for spintronics

MetalMat
Spintronics is an innovative field that exploits the intrinsic spin property of electrons instead of their charge, holding the promise of revolutionizing conventional electronic devices.
Jinyu Duan, Shuai Hu, Ping Wang, Delin Zhang, Yong Jiang   +4 more
doaj   +1 more source

Drs2p-related P-type ATPases Dnf1p and Dnf2p Are Required for Phospholipid Translocation across the Yeast Plasma Membrane and Serve a Role in Endocytosis

, 2003
Thomas Günther Pomorski, Ruben Lombardi, Howard Riezman, Philippe F. Devaux, Gerrit van Meer, Joost C. M. Holthuis   +5 more
openalex   +1 more source