Results 231 to 240 of about 8,110,093 (383)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Facile active gel-enhanced synthesis of molecular-sieving membranes with record-breaking performance. [PDF]

Sci Adv
Wu H, Yu S, Wu J, Xing W, Yu M, Zhou R.
europepmc   +1 more source

Comparative effect of indomethacin (IndoM) on the enzymes of carbohydrate metabolism, brush border membrane and oxidative stress in the kidney, small intestine and liver of rats

, 2019
Sheeba Khan, Faiz Noor Khan Yusufi, Ahad Noor Khan Yusufi   +2 more
openalex   +1 more source

Natural Organic Matter Removal and Fouling Control in Low-Pressure Membrane Filtration for Water Treatment [PDF]

, 2014
Xiaojun Cui, Kwang‐Ho Choo
openalex   +1 more source

Membrane biophysics [PDF]

Current Biology, 2006
openaire   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Biomimetic action-potential transmission via mechano-gated potassium channels assembled by quadruple hydrogen-bonded crown ethers. [PDF]

Sci Adv
Li C, Chen C, Shi J, Han W, Fu Q, Yang L.   +5 more
europepmc   +1 more source

Simulation of P systems with active membranes on CUDA [PDF]

, 2009
José M. Cecilia, José M. Garcı́a, Ginés D. Guerrero, Miguel Ángel Martínez del Amor, Ignacio Pérez–Hurtado, Mario J. Pérez-Jímenez   +5 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Safety and Feasibility of Extended Platelet-Rich Fibrin as a Solo Barrier Membrane for Ridge Preservation: A Case Series. [PDF]

Clin Exp Dent Res
Estrin NE, Tran TB, Espinoza AR, Ahmad P, Farshidfar N, Holmes R, Zhang Y, Miron RJ.   +7 more
europepmc   +1 more source