Effect of Tau Fragment and Membrane Interactions on Membrane Permeabilization and Peptide Aggregation. [PDF]
Islam M+5 more
europepmc +1 more source
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley +1 more source
Novel insights into the lipid signalling in human spermatozoa. [PDF]
Serafini S, O'Flaherty C.
europepmc +1 more source
On Simple Acute Inflammation of the Membranes of the Brain in Infants [PDF]
Rilliet
openalex +1 more source
Identifying prognostic targets in metastatic prostate cancer beyond AR
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng+13 more
wiley +1 more source
Binding of Soluble Ligands to Membrane Receptors: A Molecular Dynamics Simulation Study. [PDF]
Hou R+5 more
europepmc +1 more source
Earthing effects on mitochondrial function: ATP production and ROS generation
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley +1 more source
Two-Dimensional Nanoporous Cross-linked Polymer Networks as Emerging Candidates for Gas Adsorption
Elvin Aliyev+5 more
doaj +1 more source
Structural molecular details of the endocytic adaptor protein CALM upon binding with phosphatidylinositol 4,5-bisphosphate-containing model membranes. [PDF]
Santamaria A+12 more
europepmc +1 more source