Results 311 to 320 of about 6,904,879 (418)
Abstract Objectives An increasing body of evidence indicates altered DNA methylation in Parkinson's disease, yet the reproducibility and utility of such methylation changes are largely unexplored. We aimed to further elucidate the role of dysregulated DNA methylation in Parkinson's disease and to evaluate the biomarker potential of methylation‐based ...
Ingeborg Haugesag Lie+4 more
wiley +1 more source
From closed to open: three dynamic states of membrane-bound cytochrome P450 3A4. [PDF]
Spanke VA+3 more
europepmc +1 more source
Skin calcium deposits in primary familial brain calcification: A novel potential biomarker
Abstract Objective Primary Familial Brain Calcification (PFBC) is a rare neurodegenerative disorder characterized by small vessel calcifications in the basal ganglia. PFBC is caused by pathogenic variants in different genes and its physiopathology is still largely unknown. Skin vascular calcifications have been detected in single PFBC cases, suggesting
Aron Emmi+8 more
wiley +1 more source
Lipid packing and cholesterol content regulate membrane wetting and remodeling by biomolecular condensates. [PDF]
Mangiarotti A+6 more
europepmc +1 more source
Universal Proteomic Signature After Exercise‐Induced Muscle Injury in Muscular Dystrophies
ABSTRACT Objective Several neuromuscular disorders (NMDs) are characterized by progressive muscle damage and are marked by the elevation of circulating muscle proteins from activity‐related injury. Despite a diverse array of genetic drivers, many NMDs share similar patterns of exercise intolerance and higher concentrations of muscle injury proteins ...
Mads G. Stemmerik+5 more
wiley +1 more source
Pericyte Electrical Signalling and Brain Haemodynamics. [PDF]
Longden TA, Isaacs D.
europepmc +1 more source
Two-Dimensional Nanoporous Cross-linked Polymer Networks as Emerging Candidates for Gas Adsorption
Elvin Aliyev+5 more
doaj +1 more source
Epitope Mapping of Anti‐Neurofascin 155 Antibody in a Large Cohort of Autoimmune Nodopathy Patients
ABSTRACT Objective Autoimmune nodopathy (AN), a newly recognized disease entity, is an immune‐mediated polyneuropathy involving autoantibodies against cell adhesion molecules located in nodes of Ranvier and paranodal regions, such as neurofascin 186 (NF186) and neurofascin 155 (NF155). The present study aimed to identify the epitopes for autoantibodies
Amina A. Abdelhadi+6 more
wiley +1 more source