Results 101 to 110 of about 1,339,571 (248)

Membrane curvature at a glance [PDF]

, 2015
Membrane curvature is an important parameter in defining the morphology of cells, organelles and local membrane subdomains. Transport intermediates have simpler shapes, being either spheres or tubules.
McMahon, HT, McMahon, H.T., Boucrot, E, Boucrot, Emmanuel   +3 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

MDAnalysis MembraneCurvature Tool

<h1>Bugfix release v1.1.1 of Membrane Curvature</h1> <p>This version mostly removes erroneously packaged additional files on pypi.</p> <h2>What's Changed</h2> <ul> <li>Add deployment workflow by @IAlibay in
Barreto-Ojeda, Estefania
core   +2 more sources

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Bending the rules: curvature’s impact on cell biology

BMC Biology
Curvature is a ubiquitous feature in biology, shaping structures at every scale and playing diverse roles in processes ranging from membrane dynamics to tissue organization.
Carole Arnold, Ismail Tahmaz, Marie-Ly Chapon, Hasna Maayouf, Valeriy Luchnikov, Jean-Louis Milan, Fabricio Borghi, Laurent Pieuchot   +7 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Cholesterol Induces Uneven Curvature of Asymmetric Lipid Bilayers

The Scientific World Journal, 2013
A remarkable flexibility is observed in biological membranes, which allows them to form the structures of different curvatures. We addressed the question of intrinsic ability of phospholipid membranes to form highly curved structures and the role of ...
S. O. Yesylevskyy, A. P. Demchenko, S. Kraszewski, C. Ramseyer   +3 more
doaj   +1 more source

Membrane-Active Peptides Attack Cell Membranes in a Lipid-Regulated Curvature-Generating Mode

Membrane-active peptides (MAPs) exhibit great potential in biomedical applications due to their unique ability to overcome the cell membrane barrier.
Zhixiong Deng (10151912), Xin You (784189), Kai Yang (73590), Bing Yuan (1629931), Zhao Lin (87465), Xuewei Dong (10177907)   +5 more
core   +1 more source

Understanding membrane pore-wetting in the membrane distillation of oil emulsions via molecular dynamics simulations

, 2018
The escalating volume of oily wastewater, particularly produced water, necessitates efficient means of treatment for the recovery of both the water and oil constituents. Towards this end, membrane distillation (MD) is a promising candidate. Unfortunately,
Le Han, Velioğlu, Sadiye, Sadiye Velioğlu, Han, Le, Jia Wei Chew, Chew, Jia Wei   +5 more
core   +1 more source