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The missing link: TBK1 connects membrane damage sensing with autophagic response upon adenovirus entry [PDF]

open access: yesAutophagy Reports, 2022
Most cell entry by invading pathogens involves penetration of either the plasma membrane or the endo-lysosomal compartment to reach the cytosol. This process frequently inflicts membrane damage and provokes a cellular response.
Coralie F. Daussy   +3 more
doaj   +2 more sources

Bacterial lux-Biosensors for Detecting Specific Cell Responses to Membrane Damage [PDF]

open access: yesBiosensors
Whole-cell biosensors represent one of the tools used for assessing the effects of various agents on living cells. Here we have constructed and tested whole-cell lux-biosensors to detect membrane damage in both Gram-negative and Gram-positive bacteria ...
Vladimir A. Plyuta   +8 more
doaj   +2 more sources

Membrane Damage and Metabolic Disruption as the Mechanisms of Linalool against Pseudomonas fragi: An Amino Acid Metabolomics Study [PDF]

open access: yesFoods
Pseudomonas fragi (P. fragi) is usually detected in low-temperature meat products, and seriously threatens food safety and human health. Therefore, the study investigated the antibacterial mechanism of linalool against P.
Jiaxin Cai   +7 more
doaj   +2 more sources

Foliar Application of Melatonin Positively Affects the Physio-Biochemical Characteristics of Cotton (Gossypium hirsutum L.) under the Combined Effects of Low Temperature and Salinity Stress

open access: yesPlants, 2023
Low temperature and soil salinization during cotton sowing and seedling adversely affect cotton productivity. Exogenous melatonin (MT) can alleviate the damage caused to plants under non-biological stress; thus, applying MT is a means to improve the ...
Yuanyuan Fu   +8 more
doaj   +1 more source

Effect of Arsenic Soil Contamination on Stress Response Metabolites, 5-Methylcytosine Level and CDC25 Expression in Spinach

open access: yesToxics, 2023
Experimental spinach plants grown in soil with (5, 10 and 20 ppm) arsenic (As) contamination were sampled in 21 days after As(V) contamination. Levels of As in spinach samples (from 0.31 ± 0.06 µg g−1 to 302.69 ± 11.83 µg g−1) were higher in roots and ...
Marek Popov   +12 more
doaj   +1 more source

Mode of action of antimicrobial agents albofungins in eradicating penicillin- and cephalosporin-resistant Vibrio parahaemolyticus biofilm

open access: yesMicrobiology Spectrum, 2023
Albofungin is a promising broad-spectrum antimicrobial compound against multidrug-resistant bacteria. In the present study, we further investigated albofungin’s biofilm eradication activity and its potential mode of action against drug-resistant Vibrio ...
Weiyi She   +5 more
doaj   +1 more source

Rapid Killing and Biofilm Inhibition of Multidrug-Resistant Acinetobacter baumannii Strains and Other Microbes by Iodoindoles

open access: yesBiomolecules, 2020
Multi-drug resistant Acinetobacter baumannii is well-known for its rapid acclimatization in hospital environments. The ability of the bacterium to endure desiccation and starvation on dry surfaces for up to a month results in outbreaks of health care ...
Chaitany Jayprakash Raorane   +2 more
doaj   +1 more source

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