Results 151 to 160 of about 1,587,373 (355)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Antibiotic-persistent bacterial cells exhibiting low-level ROS are eradicated by ROS-independent membrane disruption

mBio
Bacterial persistence increases therapy duration, disease relapse, and antibiotic resistance. Mechanisms underlying persistence and feasible ways to rapidly eliminate persister cells are largely unknown.
Yanghui Ye, Yuanqing Tian, Mingxin Duan, Weiwei Zhu, Jingyun Wu, Yilin Chen, Feng Xu, Xilin Zhao, Karl Drlica, Yuzhi Hong   +9 more
doaj   +1 more source

Insights into the Mechanisms of Reuterin against Staphylococcus aureus Based on Membrane Damage and Untargeted Metabolomics. [PDF]

Foods, 2023
Sun MC, Li DD, Chen YX, Fan XJ, Gao Y, Ye H, Zhang T, Zhao C.   +7 more
europepmc   +1 more source

Efficient Replacement of Outer Leaflet Lipids of Plasma Membrane using Exogenous Lipids with Minimal Cell Damage [PDF]

, 2019
Guangtao Li, Shinako Kakuda, Pavana Suresh, Erwin London   +3 more
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Preventive Effects of a Traditional Chinese Medicine (Sho-Saiko-To) against Oxygen Toxicity and Membrane Damage during Endotoxemia.

, 1993
Shuhei Sakaguchi, E Tsutsumi, Katsushi Yokota   +2 more
openalex   +2 more sources

Experimental analysis of structural damage in tensile membranes [PDF]

, 2018
Bartolomeo Trentadue
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

DEVELOPMENT OF DAMAGE TEST APPARATUS BY TRAFFIC FOR CAR DECK WATERPROOFING MEMBRANES

, 2000
Kyoji TANAKA, Eiji Kagawa, Hiroyuki Miyauchi   +2 more
openalex   +2 more sources