Results 81 to 90 of about 1,587,373 (355)
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
A Role for Secondary Metabolites in Desiccation Tolerance in Lichens
In lichens, secondary metabolites have been shown to protect against biotic stresses such as pathogen attacks and grazing, and abiotic stresses such as ultraviolet (UV) and high photosynthetically active radiation (PAR).
Nqobile Truelove Ndhlovu +2 more
doaj +1 more source
This study evaluated the influence of Azospirillum lipoferum on the growth of Myracroduon urundeuva (Anacardiaceae) plants under drought stress, by means of biometric, physical–chemical and biochemical parameters. The association of A. lipoferum with the
Douglas Moreira de Oliveira +5 more
doaj +1 more source
Antibacterial Activity of Dihydroquercetin Separated from Fructus Polygoni orientalis against Clavibacter michiganensis subsp. sepedonicus via Damaging Cell Membrane [PDF]
Jin Cai, Shiqin Wang, Qi Wang
openalex +1 more source
A nitric oxide synthase transgene ameliorates muscular dystrophy in mdx mice. [PDF]
Dystrophin-deficient muscles experience large reductions in expression of nitric oxide synthase (NOS), which suggests that NO deficiency may influence the dystrophic pathology.
Spencer, MJ, Tidball, JG, Wehling, M
core
Punicalagin Damages the Membrane of Salmonella Typhimurium
Salmonella, a bacterial foodborne pathogen, can contaminate meat, milk, and vegetables. While appropriate measures are available to control Salmonella, the inhibitory phytochemicals from plants are gaining increased attention. Punicalagin, a natural antimicrobial, is one of the main active tannins isolated from Punica granatum L.
Guanghui Li +3 more
openaire +2 more sources
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The aim of this study was to investigate the bacterial inhibitory ability and mechanism of action of linalyl alcohol against B. thermosphacta. Linalyl alcohol causes the leakage of intracellular material by disrupting the cell wall and exposing the ...
Longteng Wang +3 more
doaj +1 more source
Objective The aim of this study was to investigate how modifications at the periphery of the porphyrin ring affect the anticancer activity of Mn porphyrins (MnPs)-based SOD mimics. Methods Six compounds: MnTE-2-PyP with a short ethyl chain on the pyridyl
Bader Hasan +3 more
doaj +1 more source
Membrane charge and lipid packing determine polymyxin-induced membrane damage
AbstractWith the advent of polymyxin B (PmB) resistance in bacteria, the mechanisms for mcr-1 resistance are of crucial importance in the design of novel therapeutics. The mcr-1 phenotype is known to decrease membrane charge and increase membrane packing by modification of the bacterial outer membrane.
Adree Khondker +6 more
openaire +2 more sources

