Results 41 to 50 of about 1,241,158 (299)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Mechanism of Silica Nanoparticle-Induced Particulate Fouling in Vacuum Membrane Distillation
MembranesMembrane distillation (MD) is a process driven by the vapor pressure difference dependent on temperature variation, utilizing a hydrophobic porous membrane. MD operates at low pressure and temperature, exhibiting resilience to osmotic pressure.
Yejin Lee +3 more
doaj +1 more source
Membranes, 2019 A composite, three-layered membrane for membrane distillation was prepared from electrospun polyvinylidene fluoride (PVDF) nanofibers supported by commercial polyethersulfone (PES) nanofiber based nonwoven from E.I.
Mustafa Al-Furaiji +5 more
doaj +1 more source
, 2018 The escalating volume of oily wastewater, particularly produced water, necessitates efficient means of treatment for the recovery of both the water and oil constituents. Towards this end, membrane distillation (MD) is a promising candidate. Unfortunately,
Le Han +5 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Research of conductive membrane distillation
Gongye shui chuliMembrane distillation is an energy-saving technology that utilizes low-grade energy to treat highly saline water, however, the current use of the technology is faced with serious membrane fouling, wetting and other problems.
ZHANG Lengwei +3 more
doaj +1 more source
Polyurethane Nanofiber Membranes for Waste Water Treatment by Membrane Distillation
, 2017 Self-sustained electrospun polyurethane nanofiber membranes were manufactured and tested on a direct-contact membrane distillation unit in an effort to find the optimum membrane thickness to maximize flux rate and minimize heat losses across the membrane.
Lederer Tomáš +2 more
core +1 more source