Results 211 to 220 of about 8,606 (251)

Membrane fluidity as an index of pathology

Medical Hypotheses, 1982
Abstract Cell membrane fluidity (CMF) is a parameter crucial to the maintenance of cellular function. Alterations in CMF are seen in several pandemic disease processes and the normalization of CMF in these diseases may prove therapeutic.
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Membrane Fluidity and Cellular Functions

1975
An area of intense current interest in molecular and cell biology is the structure of biological membranes. A great change in our picture of membranes has occurred in the last few years, and there is now fairly widespread acceptance of a model for the organization of the lipids and proteins of membranes called the “fluid mosaic model” (Singer and ...
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Phenytoin and Membrane Fluidity in Myotonic Dystrophy

Archives of Neurology, 1975
Electron spin resonance spectroscopy was used to substantiate the presence of a membrane defect in myotonic erythrocytes. There was increased membrane fluidity and decreased polarity in myotonic membranes. Phenytoin (formerly diphenylhydantoin) "normalizes" fluidity differences in spectra derived from myotonic erythrocytes but has no significant effect
A D, Roses, A, Butterfield, S H, Appel, D B, Chestnut   +3 more
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Effects of Hyperforin on the Fluidity of Brain Membranes

Pharmacopsychiatry, 2001
Hyperforin, an acylphloroglucinol derivative isolated from Hypericum perforatum (St. John's wort, SJW), affects several ionic conductance mechanisms in brain cells by an as yet unknown mechanism. We tested the effects of hyperforin on the fluidity of crude brain membranes from young guinea pigs.
G P, Eckert, W E, Müller
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Membrane fluidity as affected by the insecticide lindane

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1989
Fluorescence polarization of 1,6-diphenyl-1,3,5-hexatriene (DPH) was used to study the interaction of lindane with model and native membranes. Lindane disorders the gel phase of liposomes reconstituted with dimyristoyl-, dipalmitoyl- and distearoylphosphatidylcholines (DMPC, DPPC and DSPC), since it broadens and shifts the main phase transition, but no
M C, Antunes-Madeira, V M, Madeira
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Effects of trace elements on membrane fluidity

Journal of Trace Elements in Medicine and Biology, 2005
According to the Fluid Mosaic Model, a biological membrane is a two-dimensional fluid of oriented proteins and lipids. The lipid bilayer is the basic structure of all cell and organelle membranes. Cell membranes are dynamic, fluid structures, and most of their molecules are able to move in the plane of the membrane.
José Joaquín, Garcia, E, Martínez-Ballarín, S, Millán-Plano, J L, Allué, C, Albendea, L, Fuentes, J F, Escanero   +6 more
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Fluidity of Membrane Lipids

1984
In considering the various fatty acids that occur in living cells, we have questioned whether or not unsaturated fatty acids serve only to establish membrane fluidity. If this were their only role, then the wide variety of acyl structures that occurs in nature seems unnecessary since oleate (cis-9–18: 1) or palmitoleate (cis-9–16:1) appears capable of ...
William E. M. Lands, Frank S. Davis
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Membrane Fluidity and Membrane Activities

1985
Observations that changes in membrane fluidity affect a wide variety of membrane and cellular activities 1–5 greatly stimulated interest in the study of membrane fluidity. It also suggested that such effects could be used to monitor such changes. In this chapter I will discuss selected examples of cases in which membrane fluidity seems to affect ...
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Platelet membrane fluidity

Neurology, 1993
Walter A. Kukull, Thomas R. Hinds
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Membrane fluidity

General Pharmacology: The Vascular System, 1986
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