Results 211 to 220 of about 56,553 (257)

Membrane Fluidity and Alcohol Dependence

Alcoholism: Clinical and Experimental Research, 1986
Rats were chronically intoxicated with alcohol by exposing them to increasing concentrations of ethanol vapor over a 4‐week period. They were tested for alcohol consumption in a free choice situation of water and 10% (v/v) alcohol. On the basis of their intakes they were divided into alcohol‐dependent and nondependent groups.
B, Le Bourhis, F, Beaugé, G, Aufrère, R, Nordmann   +3 more
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Fluidity of Thyroid Plasma Membranes

1988
The main function of the thyroid cell is the secretion of thyroid hormones (T4, thyroxine; T3, triiodothyronine). Thyroid hormones are first synthesized as part of thyroglobulin. Newly synthesized thyroglobulin is iodinated and vectorially transported to the apical region of the cell and released for storage in the lumen by exocytosis.
H, Depauw, M, De Wolf, G, Van Dessel, H, Hilderson, A, Lagrou, W, Dierick   +5 more
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The Effects of Drugs on Membrane Fluidity

Annual Review of Pharmacology and Toxicology, 1984
Anesthetics almost always disorder or "fluidize" membranes, i.e. the drugs increase the mobility of spin labels and reduce order parameters. This effect is universal at high concentrations above the clinical range, but in some kinds of membranes low concentrations of drugs have an ordering effect.
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Membrane Fluidity and Cancer Metastasis

Experimental Cell Biology, 2008
The membrane fluidity of murine B16 melanoma and L5178 lymphoma variants is examined in relation to their metastatic potential. A higher lateral mobility of membrane proteins in metastasis is indicated by lectin receptor-mediated agglutination studies, but these do not constitute incontrovertible evidence that higher fluidity might be relevant in the ...
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Cell membrane fluidity and prostaglandins

Medical Hypotheses, 1981
Abstract It is proposed that prostaglandins may bring about some of their actions by altering cell membrane fluidity.
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Membrane fluidity as an index of pathology

Medical Hypotheses, 1982
Abstract Cell membrane fluidity (CMF) is a parameter crucial to the maintenance of cellular function. Alterations in CMF are seen in several pandemic disease processes and the normalization of CMF in these diseases may prove therapeutic.
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Membrane fluidity as affected by the insecticide lindane

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1989
Fluorescence polarization of 1,6-diphenyl-1,3,5-hexatriene (DPH) was used to study the interaction of lindane with model and native membranes. Lindane disorders the gel phase of liposomes reconstituted with dimyristoyl-, dipalmitoyl- and distearoylphosphatidylcholines (DMPC, DPPC and DSPC), since it broadens and shifts the main phase transition, but no
M C, Antunes-Madeira, V M, Madeira
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Membrane Fluidity and Cellular Functions

1975
An area of intense current interest in molecular and cell biology is the structure of biological membranes. A great change in our picture of membranes has occurred in the last few years, and there is now fairly widespread acceptance of a model for the organization of the lipids and proteins of membranes called the “fluid mosaic model” (Singer and ...
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Phenytoin and Membrane Fluidity in Myotonic Dystrophy

Archives of Neurology, 1975
Electron spin resonance spectroscopy was used to substantiate the presence of a membrane defect in myotonic erythrocytes. There was increased membrane fluidity and decreased polarity in myotonic membranes. Phenytoin (formerly diphenylhydantoin) "normalizes" fluidity differences in spectra derived from myotonic erythrocytes but has no significant effect
A D, Roses, A, Butterfield, S H, Appel, D B, Chestnut   +3 more
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Effects of Hyperforin on the Fluidity of Brain Membranes

Pharmacopsychiatry, 2001
Hyperforin, an acylphloroglucinol derivative isolated from Hypericum perforatum (St. John's wort, SJW), affects several ionic conductance mechanisms in brain cells by an as yet unknown mechanism. We tested the effects of hyperforin on the fluidity of crude brain membranes from young guinea pigs.
G P, Eckert, W E, Müller
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