Results 71 to 80 of about 8,606 (251)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Membrane fluidity adjustments in ethanol-stressed Oenococcus oeni cells

, 2003
The effect of ethanol on the cytoplasmic membrane of Oenococcus oeni cells and the role of membrane changes in the acquired tolerance to ethanol were investigated.
Silveira, M.G., da, Rombouts, F.M., Abee, T., Golovina, E.A., da Silveira, M.G., Hoekstra, F.A.   +5 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Environmental influences on organotin-yeast interactions [PDF]

, 2002
As a consequence of the widespread industrial and agricultural applications of organotin compounds, contamination of various ecosystems has occurred in recent decades.
White, Jane S.
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Membrane effects of Cocoa Procyanidins in Liposomes and Jurkat T Cells

Biological Research, 2004
We investigated the effects of the interaction between flavanols and related procyanidins (dimer to hexamer) with both cell and synthetic membranes, on bilayer fluidity and susceptibility to oxidation.
SANDRA V. VERSTRAETEN, PATRICIA I. OTEIZA, CÉSAR G. FRAGA   +2 more
doaj  

The lipid composition and membrane fluidity of Dictyostelium discoideum plasma membranes at various stages during differentiation.

Journal of Lipid Research, 1980
There are only minor changes in the amounts of the major lipid constituents of Dictyostelium discoideum plasma membranes during the early stages in the differentiation of this organism.
G Weeks, F G Herring
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Turning Up the Heat on Membrane Fluidity

, 2015
How do cells maintain the fluidity of cellular membrane in response to temperature fluctuation? In this issue of Cell, Ma et al. identify a regulatory circuit involving a heat-induced acyl-CoA dehydrogenase that controls the lipid saturation level and ...
Fan, Weiwei, Evans, Ronald M.
core   +1 more source

Membrane fluidity and membrane fusion [PDF]

Biochemical Journal, 1972
J I, Howell, Q F, Ahkong, F C, Cramp, D, Fisher, W, Tampion, J A, Lucy   +5 more
openaire   +2 more sources