Results 81 to 90 of about 8,606 (251)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Membrane fluidity determines sensitivity of filamentous fungi to chitosan [PDF]

, 2010
The antifungal mode of action of chitosan has been studied for the last 30 years, but is still little understood. We have found that the plasma membrane forms a barrier to chitosan in chitosan-resistant but not chitosan-sensitive fungi.
J.A. Lopez-Jimenez, J. Palma-Guerrero, I.‐C. Huang, López Jiménez, José Ángel, Jansson, H.B., Lopez-Llorca, L. V., I.-C. Huang, J. Palma‐Guerrero, Jansson, H. B., Palma-Guerrero, J., Villalaín, J., J. A. Lopez‐Jimenez, H.‐B. Jansson, N. D. Read, Lopez-Jimenez, J. A., Palma Guerrero, J., Pérez-Berná, A. J., A.J. Pérez-Berná, A. J. Pérez‐Berná, Pérez Berná, A. J., J. Salinas, L. V. Lopez‐Llorca, J. Villalaín, L.V. Lopez-Llorca, Read, N. D., N.D. Read, Read, N.D., H.-B. Jansson, López Llorca, L. V., J. Villalaín, Huang, I. C., Salinas, J.   +31 more
core   +1 more source

Differential effects of lysophospholipid headgroups, acyl chain length and saturation on vacuole acidification, Ca2+ transport, membrane fluidity, and fusion

Frontiers in Cell and Developmental Biology
SNARE-mediated membrane fusion is regulated by the lipid composition of the engaged bilayers. Lipids impact fusion through direct protein-lipid interactions or through modulating the physical properties of membranes to affect protein function ...
Chi Zhang, Yilin Feng, Jorge D. Calderin, Vito Failla, Adam Balutowski, Razeen Ahmed, Charlie Knapp, Ved Shah, Daniel Grudzien, Jahnavi M. Karat, Elliel Foley, Rutilio A. Fratti, Rutilio A. Fratti   +12 more
doaj   +1 more source

Membrane fluidity and hypertension [PDF]

American Journal of Hypertension, 2003
Kazushi, Tsuda, Ichiro, Nishio
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Investigating Membrane Fluidity in Two-dimensions

, 2020
Biological membranes allow for compartmentalization within cells, membranes possess unique, complex chemical and morphological features, thus proving it difficult to investigate the processes that occur at the membrane interface.
Chand, Sarina
core  

Effects of Alcohol on Membrane Fluidity of Human Erythrocyte

, 1994
Membrane fluidity in human erythrocytes was measured by a spin label method using an electron spin resonance spectrometer in healthy volunteers after ingestion of alcohol (1.5 ml of whisky/kg body weight).
Miyagawa, Fumio, Koide, Yayoi, Toda, Naomi, Hiramatsu, Midori, Mori, Ichiya   +4 more
core   +1 more source

Phase separation of the plasma membrane in human red blood cells as a potential tool for diagnosis and progression monitoring of type 1 diabetes mellitus.

PLoS ONE, 2017
Glycosylation, oxidation and other post-translational modifications of membrane and transmembrane proteins can alter lipid density, packing and interactions, and are considered an important factor that affects fluidity variation in membranes.
Giuseppe Maulucci, Ermanno Cordelli, Alessandro Rizzi, Francesca De Leva, Massimiliano Papi, Gabriele Ciasca, Daniela Samengo, Giovambattista Pani, Dario Pitocco, Paolo Soda, Giovanni Ghirlanda, Giulio Iannello, Marco De Spirito   +12 more
doaj   +1 more source

Plant-Unique cis/trans Isomerism of Long-Chain Base Unsaturation is Selectively Required for Aluminum Tolerance Resulting from Glucosylceramide-Dependent Plasma Membrane Fluidity

Plants, 2019
Cis/trans isomerism of the Δ8 unsaturation of long-chain base (LCB) is found only in plant sphingolipids. This unique geometry is generated by sphingolipid LCB Δ8 desaturase SLD which produces both isomers at various ratios, resulting in ...
Masaya Sato, Minoru Nagano, Song Jin, Atsuko Miyagi, Masatoshi Yamaguchi, Maki Kawai-Yamada, Toshiki Ishikawa   +6 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source