Results 171 to 180 of about 66,049 (287)

Direct grafting of tetraaniline via perfluorophenylazide photochemistry to create antifouling, low bio-adhesion surfaces. [PDF]

, 2019
Conjugated polyaniline has shown anticorrosive, hydrophilic, antibacterial, pH-responsive, and pseudocapacitive properties making it of interest in many fields. However, in situ grafting of polyaniline without harsh chemical treatments is challenging. In
Aguilar, Stephanie, Chen, Dayong, Curson, Paige A, He, Na, Hoek, Eric MV, Huang, Shu-Chuan, Huang, Xinwei, Jun, Dukwoo, Kaner, Richard B, Lin, Cheng-Wei, Mak, Wai H, McVerry, Brian T, Rao, Ethan   +12 more
core  

A case study showing the role of hydrophobicity variants and other enriched mAb proteoforms on filterability through a virus filter with productivity improvement measures

Biotechnology Progress, EarlyView.
Abstract A rapid assessment of manufacturability for drug candidates is crucial for advancing a prospective biotherapeutic from a candidate to a bulk drug substance. A lot‐to‐lot approach to manufacturability is adopted where each biologic batch is assessed for manufacturability as a bulk, unfractionated pool.
Solomon Isu, Derek Silva, Melissa Holstein, Angela Lewandowski, Kristina Cunningham, Adam Sokolnicki, Bala Raghunath   +6 more
wiley   +1 more source

Application of Optical Coherence Tomography (OCT) to Analyze Membrane Fouling under Intermittent Operation. [PDF]

Membranes (Basel), 2023
Lee S, Cho H, Choi Y, Lee S.
europepmc   +1 more source

Performance of large virus removal filters during AAV processing: Influence of flux and process disruptions

Biotechnology Progress, EarlyView.
Abstract As adeno‐associated viral vectors (AAV) continue to advance through the clinical pipeline, effective downstream purification strategies must be developed to ensure bulk drug purity and safety. AAV are produced within mammalian cells, bringing forth risks associated with viral contamination.
Akshay S. Chaubal, Asingsa W. Arachchige, Annabelle J. Zahn, S. Ranil Wickramasinghe, Xianghong Qian, Andrew L. Zydney   +5 more
wiley   +1 more source

Reduction of Ultrafiltration Membrane Fouling by the Pretreatment Removal of Emerging Pollutants: A Review. [PDF]

Membranes (Basel), 2023
Zhang J, Li G, Yuan X, Li P, Yu Y, Yang W, Zhao S.   +6 more
europepmc   +1 more source

Design of experiments‐guided membrane capture facilitates integration of continuous virus inactivation using Phi6 as a surrogate virus in an intensified downstream process

Biotechnology Progress, EarlyView.
Abstract The growing demand for cost‐efficient and flexible biomanufacturing has increased interest in process‐intensified downstream platforms. This study evaluates an intensified monoclonal antibody (mAb) purification sequence, where two unit operations traditionally performed in batch mode—Protein A capture and low pH virus inactivation (VI)—are ...
Mario Grünberg, Lisa Lipski, Gabriel Fisicaro, Thomas Duvignau, Karolina Meyer‐Heinrichs, Diana Carmen Mocsy, Thomas‐Josef Filz, Bastian Quaas, Alexandra Stützer   +8 more
wiley   +1 more source

Membrane Fouling Prediction Based on Tent-SSA-BP. [PDF]

Membranes (Basel), 2022
Ling G, Wang Z, Shi Y, Wang J, Lu Y, Li L.   +5 more
europepmc   +1 more source

Perigraftitis, an independent biologic complication associated with implants placed in grafted bone

Clinical Advances in Periodontics, EarlyView.
Abstract Background Perigraftitis is a recently introduced concept describing biologic complications specifically associated with implants placed in grafted bone. It is characterized by inflammation resulting from bacterial colonization of grafted bone and/or residual graft particulates.
Jonathan H. Do, Charles M. Cobb, John T. Shen   +2 more
wiley   +1 more source

Differences in the Effect of Mn²⁺ on the Reverse Osmosis Membrane Fouling Caused by Different Types of Organic Matter: Experimental and Density Functional Theory Evidence. [PDF]

Membranes (Basel), 2023
Gao Q, Duan L, Jia Y, Zhang H, Liu J, Yang W.   +5 more
europepmc   +1 more source

Fouling of nanofiltration membranes [PDF]

Membrane Technology, 1998
openaire   +3 more sources