Results 151 to 160 of about 556,464 (304)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Light-Controlled Membrane Fusion in Synthetic Cells. [PDF]

Life (Basel)
Xu B, Caliari A, Xu J.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Molecular mechanism of cholesterol-dependent membrane fusion in SARS-CoV-2 entry. [PDF]

Signal Transduct Target Ther
Li W, Wu M, Feng S, Su J, Niu Q, Lin W, Fan J, Cui L, Xiang Y, Li H, Li K, Su Z, Lu G, Lai Y.   +13 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

From Population Averaging to Single Event Resolution: Evolution of Sensing Platforms for Membrane Fusion. [PDF]

Sensors (Basel)
Feng Y, Zhao X, Sun Z, Lou Z, Zhang S.
europepmc   +1 more source

Characterization of AtCDC48. Evidence for Multiple Membrane Fusion Mechanisms at the Plane of Cell Division in Plants [PDF]

, 2002
David M. Rancour, Carrie E. Dickey, Sookhee Park, Sebastian Y. Bednarek   +3 more
openalex   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Tracking the protein conformational motions driving HIV-1 membrane fusion. [PDF]

Sci Rep
Unarta IC, Crotzer S, Gnanakaran S.
europepmc   +1 more source

Coronavirus-Induced Membrane Fusion Requires the Cysteine-Rich Domain in the Spike Protein

, 2000
Kevin W. Chang, YiWei Sheng, James L. Gombold   +2 more
openalex   +2 more sources