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Incorporation of Spike and Membrane Glycoproteins into Coronavirus Virions [PDF]

Viruses, 2015
The envelopes of coronaviruses (CoVs) contain primarily three proteins; the two major glycoproteins spike (S) and membrane (M), and envelope (E), a non-glycosylated protein.
Makoto Ujike, Fumihiro Taguchi
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Two Sides to Every Story: Herpes Simplex Type-1 Viral Glycoproteins gB, gD, gH/gL, gK, and Cellular Receptors Function as Key Players in Membrane Fusion

Viruses, 2021
Herpes simplex virus type-1 (HSV-1) and type-2 (HSV-2) are prototypical alphaherpesviruses that are characterized by their unique properties to infect trigeminal and dorsal root ganglionic neurons, respectively, and establish life-long latent infections.
Nithya Jambunathan, Carolyn M. Clark, Farhana Musarrat, Vladimir N. Chouljenko, Jared Rudd, Konstantin G. Kousoulas   +5 more
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Glycan structures contain information for the spatial arrangement of glycoproteins in the plasma membrane. [PDF]

PLoS ONE, 2013
Glycoconjugates at the cell surface are crucial for cells to communicate with each other and the extracellular microenvironment. While it is generally accepted that glycans are vectorial biopolymers, their information content is unclear.
M Kristen Hall, Douglas A Weidner, Jian ming Chen, Christopher J Bernetski, Ruth A Schwalbe   +4 more
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Tamoxifen-resistant breast cancer cells exhibit reactivity with Wisteria floribunda agglutinin.

PLoS ONE, 2022
Glycosylation is one of the most important post-translational modifications of cell surface proteins involved in the proliferation, metastasis and treatment resistance of cancer cells.
May Thinzar Hlaing, Yoshiya Horimoto, Kaori Denda-Nagai, Haruhiko Fujihira, Miki Noji, Hiroyuki Kaji, Azusa Tomioka, Yumiko Ishizuka, Harumi Saeki, Atsushi Arakawa, Mitsue Saito, Tatsuro Irimura   +11 more
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Structures of the Hepaci-, Pegi-, and Pestiviruses envelope proteins suggest a novel membrane fusion mechanism.

PLoS Biology, 2023
Enveloped viruses encode specialised glycoproteins that mediate fusion of viral and host membranes. Discovery and understanding of the molecular mechanisms of fusion have been achieved through structural analyses of glycoproteins from many different ...
Michael R Oliver, Kamilla Toon, Charlotte B Lewis, Stephen Devlin, Robert J Gifford, Joe Grove   +5 more
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Neutrophil azurophilic granule glycoproteins are distinctively decorated by atypical pauci- and phosphomannose glycans

Communications Biology, 2021
Reiding et al. performed conventional proteomics as well as glycoproteomics on protein extracts from lysates of pooled neutrophils obtained from ten healthy donors.
Karli R. Reiding, Yu-Hsien Lin, Floris P. J. van Alphen, Alexander B. Meijer, Albert J. R. Heck   +4 more
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Antibody binding reports spatial heterogeneities in cell membrane organization

Nature Communications, 2023
The spatial organization of cell membrane glycoproteins and glycolipids is critical for mediating the binding of ligands, receptors, and macromolecules on the plasma membrane.
Daniel P. Arnold, Yaxin Xu, Sho C. Takatori   +2 more
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Fluorescent Staining of Glycoproteins on Polyvinylidene Difluoride Membrane with 8-Aminonaphthalene-1,3,6-Trisulfonate

BioTechniques, 2001
Here, we describe a simple and sensitive method that allows fluorescent detection of glycoproteins on polyvinylidene difluoride (PVDF) membrane. We used periodic acid oxidation of carbohydrate chains of glycoproteins and fluorescent labeling with 8 ...
F.Y. Che, J.F. Song, L.R. Yu, K.Y. Wang, Q.C. Xia   +4 more
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Human galectin-1 and galectin-3 promote Tropheryma whipplei infection

Gut Microbes, 2021
Tropheryma whipplei, is an actinobacterium that causes different infections in humans, including Whipple’s disease. The bacterium infects and replicates in macrophages, leading to a Th2-biased immune response. Previous studies have shown that T. whipplei
Diyoly Ayona, Sandra Madariaga Zarza, Ludovic Landemarre, Benoît Roubinet, Philippe Decloquement, Didier Raoult, Pierre-Edouard Fournier, Benoit Desnues   +7 more
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Lipidomimetic Compounds Act as HIV-1 Entry Inhibitors by Altering Viral Membrane Structure

Frontiers in Immunology, 2018
The envelope of Human Immunodeficiency Virus type 1 (HIV-1) consists of a liquid-ordered membrane enriched in raft lipids and containing the viral glycoproteins.
Jon Ander Nieto-Garai, Bärbel Glass, Carmen Bunn, Matthias Giese, Gary Jennings, Beate Brankatschk, Beate Brankatschk, Sameer Agarwal, Sameer Agarwal, Kathleen Börner, F. Xabier Contreras, F. Xabier Contreras, Hans-Joachim Knölker, Hans-Joachim Knölker, Claudia Zankl, Claudia Zankl, Kai Simons, Cornelia Schroeder, Cornelia Schroeder, Cornelia Schroeder, Maier Lorizate, Hans-Georg Kräusslich   +21 more
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