Incorporation of Spike and Membrane Glycoproteins into Coronavirus Virions [PDF]
Viruses, 2015 The envelopes of coronaviruses (CoVs) contain primarily three proteins; the two major glycoproteins spike (S) and membrane (M), and envelope (E), a non-glycosylated protein.
Makoto Ujike, Fumihiro Taguchi
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Influenza hemagglutinin and neuraminidase membrane glycoproteins. [PDF]
J Biol Chem, 2010 Considerable progress has been made toward understanding the structural basis of the interaction of the two major surface glycoproteins of influenza A virus with their common ligand/substrate: carbohydrate chains terminating in sialic acid.
Gamblin SJ, Skehel JJ.
europepmc +6 more sources
Lysosomal membrane glycoproteins bind cholesterol and contribute to lysosomal cholesterol export. [PDF]
Elife, 2016 LAMP1 and LAMP2 proteins are highly abundant, ubiquitous, mammalian proteins that line the lysosome limiting membrane, and protect it from lysosomal hydrolase action. LAMP2 deficiency causes Danon’s disease, an X-linked hypertrophic cardiomyopathy. LAMP2
Li J, Pfeffer SR.
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Glycomic analysis of membrane glycoproteins with bisecting glycosylation from ovarian cancer tissues reveals novel structures and functions. [PDF]
J Proteome Res, 2015 Biomarkers capable of detecting and targeting epithelial ovarian cancer cells for diagnostics and therapeutics would be extremely valuable. Ovarian cancer is the deadliest reproductive malignancy among women in the U.S., killing over 14 000 women each ...
Allam H +6 more
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Linkage of a membrane skeleton to integral membrane glycoproteins in human platelets. Identification of one of the glycoproteins as glycoprotein Ib. [PDF]
Journal of Clinical Investigation, 1985 Experiments were performed to determine whether platelets contain a membrane skeleton. Platelets were labeled by a sodium periodate/sodium [3H]borohydride method and lysed with Triton X-100. Much of the filamentous actin could be sedimented at low g forces (15,600 g, 4 min), but some of the actin filaments required high-speed centrifugation for their ...
J. Fox
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Paramyxovirus Glycoproteins and the Membrane Fusion Process [PDF]
Current Clinical Microbiology Reports, 2016 The family Paramyxoviridae includes many viruses that significantly affect human and animal health. An essential step in the paramyxovirus life cycle is viral entry into host cells, mediated by virus-cell membrane fusion.
Hector C. Aguilar +3 more
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Cell membrane glycan contents are biochemical factors that constitute a kinetic barrier to viral particle uptake in a protein-nonspecific manner [PDF]
eLifeVarious types of glycoproteins have been suggested to inhibit viral infection of cells via steric repulsion. However, it is difficult to evaluate such physical actions genetically, simply because they are nonspecific and can be caused by any molecule ...
Yoshihisa Kaizuka, Rika Machida
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Crosslinking of the Glycoproteins in Human Erythrocyte Membranes [PDF]
Proceedings of the National Academy of Sciences, 1974 The glycoproteins of human erythrocyte membranes were crosslinked with dimethyl adipimidate dihydrochloride. On sodium dodecyl sulfate-polyacrylamide gel electrophoregrams of the crosslinked solubilized membranes, at least three new glycoprotein complexes appeared in addition to the normal glycoprotein species. One of the new glycoprotein complexes was
Tae H. Ji
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The formation of Ca++-dependent complexes of platelet membrane glycoproteins IIb and IIIa in solution as determined by crossed immunoelectrophoresis. [PDF]
Blood, 1981 T. Kunicki +3 more
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Thrombin-induced changes in platelet membrane glycoproteins Ib, IX, and IIb-IIIa complex. [PDF]
Blood, 1987 A. Michelson, M. Barnard
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