Results 11 to 20 of about 2,350,953 (316)

Tamoxifen-resistant breast cancer cells exhibit reactivity with Wisteria floribunda agglutinin.

PLoS ONE, 2022
Glycosylation is one of the most important post-translational modifications of cell surface proteins involved in the proliferation, metastasis and treatment resistance of cancer cells.
May Thinzar Hlaing, Yoshiya Horimoto, Kaori Denda-Nagai, Haruhiko Fujihira, Miki Noji, Hiroyuki Kaji, Azusa Tomioka, Yumiko Ishizuka, Harumi Saeki, Atsushi Arakawa, Mitsue Saito, Tatsuro Irimura   +11 more
doaj   +1 more source

Structures of the Hepaci-, Pegi-, and Pestiviruses envelope proteins suggest a novel membrane fusion mechanism.

PLoS Biology, 2023
Enveloped viruses encode specialised glycoproteins that mediate fusion of viral and host membranes. Discovery and understanding of the molecular mechanisms of fusion have been achieved through structural analyses of glycoproteins from many different ...
Michael R Oliver, Kamilla Toon, Charlotte B Lewis, Stephen Devlin, Robert J Gifford, Joe Grove   +5 more
doaj   +1 more source

Neutrophil azurophilic granule glycoproteins are distinctively decorated by atypical pauci- and phosphomannose glycans

Communications Biology, 2021
Reiding et al. performed conventional proteomics as well as glycoproteomics on protein extracts from lysates of pooled neutrophils obtained from ten healthy donors.
Karli R. Reiding, Yu-Hsien Lin, Floris P. J. van Alphen, Alexander B. Meijer, Albert J. R. Heck   +4 more
doaj   +1 more source

Antibody binding reports spatial heterogeneities in cell membrane organization

Nature Communications, 2023
The spatial organization of cell membrane glycoproteins and glycolipids is critical for mediating the binding of ligands, receptors, and macromolecules on the plasma membrane.
Daniel P. Arnold, Yaxin Xu, Sho C. Takatori   +2 more
doaj   +1 more source

Super-resolution microscopy reveals specific recruitment of HIV-1 envelope proteins to viral assembly sites dependent on the envelope C-terminal tail [PDF]

, 2013
The inner structural Gag proteins and the envelope (Env) glycoproteins of human immunodeficiency virus (HIV-1) traffic independently to the plasma membrane, where they assemble the nascent virion. HIV-1 carries a relatively low number of glycoproteins in
Heilemann, Mike, Kräusslich, Hans-Georg, Malkusch, Sebastian, Muranyi, Walter, Müller, Barbara   +4 more
core   +14 more sources

Fluorescent Staining of Glycoproteins on Polyvinylidene Difluoride Membrane with 8-Aminonaphthalene-1,3,6-Trisulfonate

BioTechniques, 2001
Here, we describe a simple and sensitive method that allows fluorescent detection of glycoproteins on polyvinylidene difluoride (PVDF) membrane. We used periodic acid oxidation of carbohydrate chains of glycoproteins and fluorescent labeling with 8 ...
F.Y. Che, J.F. Song, L.R. Yu, K.Y. Wang, Q.C. Xia   +4 more
doaj   +1 more source

Fusion of Sendai virus with the target cell membrane is required for T cell cytotoxicity [PDF]

, 1978
INFECTION of mice with viruses can generate cytotoxic T lymphocytes (CTL) which show restricted specificity for target cell lysis. Specific lysis requires that the virus used to prime the target cells must be of the same type as that used to sensitise ...
A Munro, A Scheid, H Tozawa, JW Schrader, K Sugamura, M Homma, MARY-JANE GETHING, MICHAEL WATERFIELD, RM Zinkernagel, U Koszinowski, U Koszinowski, ULRICH KOSZINOWSKI, Y Hosaka   +12 more
core   +1 more source

Lipidomimetic Compounds Act as HIV-1 Entry Inhibitors by Altering Viral Membrane Structure

Frontiers in Immunology, 2018
The envelope of Human Immunodeficiency Virus type 1 (HIV-1) consists of a liquid-ordered membrane enriched in raft lipids and containing the viral glycoproteins.
Jon Ander Nieto-Garai, Bärbel Glass, Carmen Bunn, Matthias Giese, Gary Jennings, Beate Brankatschk, Beate Brankatschk, Sameer Agarwal, Sameer Agarwal, Kathleen Börner, F. Xabier Contreras, F. Xabier Contreras, Hans-Joachim Knölker, Hans-Joachim Knölker, Claudia Zankl, Claudia Zankl, Kai Simons, Cornelia Schroeder, Cornelia Schroeder, Cornelia Schroeder, Maier Lorizate, Hans-Georg Kräusslich   +21 more
doaj   +1 more source

Human galectin-1 and galectin-3 promote Tropheryma whipplei infection

Gut Microbes, 2021
Tropheryma whipplei, is an actinobacterium that causes different infections in humans, including Whipple’s disease. The bacterium infects and replicates in macrophages, leading to a Th2-biased immune response. Previous studies have shown that T. whipplei
Diyoly Ayona, Sandra Madariaga Zarza, Ludovic Landemarre, Benoît Roubinet, Philippe Decloquement, Didier Raoult, Pierre-Edouard Fournier, Benoit Desnues   +7 more
doaj   +1 more source

Tomato spotted wilt virus glycoproteins induce the formation of endoplasmic reticulum- and Golgi-derived pleomorphic membrane structures in plant cells [PDF]

, 2008
Tomato spotted wilt virus (TSWV) particles are spherical and enveloped, an uncommon feature among plant infecting viruses. Previous studies have shown that virus particle formation involves the enwrapment of ribonucleoproteins with viral glycoprotein ...
Denecke, J., Foresti, O., Goldbach, R.W., Kormelink, R.J.M., Ribeiro, D.M.O.G., Wellink, J.   +5 more
core   +2 more sources