Results 11 to 20 of about 133,090 (338)

Antibody binding reports spatial heterogeneities in cell membrane organization [PDF]

open access: yesNature Communications, 2023
The spatial organization of cell membrane glycoproteins and glycolipids is critical for mediating the binding of ligands, receptors, and macromolecules on the plasma membrane.
Daniel P. Arnold   +2 more
doaj   +2 more sources

Incorporation of Spike and Membrane Glycoproteins into Coronavirus Virions [PDF]

open access: yesViruses, 2015
The envelopes of coronaviruses (CoVs) contain primarily three proteins; the two major glycoproteins spike (S) and membrane (M), and envelope (E), a non-glycosylated protein.
Makoto Ujike, Fumihiro Taguchi
doaj   +2 more sources

Influenza hemagglutinin and neuraminidase membrane glycoproteins. [PDF]

open access: yesJ Biol Chem, 2010
Considerable progress has been made toward understanding the structural basis of the interaction of the two major surface glycoproteins of influenza A virus with their common ligand/substrate: carbohydrate chains terminating in sialic acid. The specificity of virus attachment to target cells is mediated by hemagglutinin, which acquires characteristic ...
Gamblin SJ, Skehel JJ.
europepmc   +5 more sources

Crosslinking of the Glycoproteins in Human Erythrocyte Membranes [PDF]

open access: greenProceedings of the National Academy of Sciences, 1974
The glycoproteins of human erythrocyte membranes were crosslinked with dimethyl adipimidate dihydrochloride. On sodium dodecyl sulfate-polyacrylamide gel electrophoregrams of the crosslinked solubilized membranes, at least three new glycoprotein complexes appeared in addition to the normal glycoprotein species. One of the new glycoprotein complexes was
Tae H. Ji
openalex   +4 more sources

Two Sides to Every Story: Herpes Simplex Type-1 Viral Glycoproteins gB, gD, gH/gL, gK, and Cellular Receptors Function as Key Players in Membrane Fusion

open access: yesViruses, 2021
Herpes simplex virus type-1 (HSV-1) and type-2 (HSV-2) are prototypical alphaherpesviruses that are characterized by their unique properties to infect trigeminal and dorsal root ganglionic neurons, respectively, and establish life-long latent infections.
Nithya Jambunathan   +5 more
doaj   +1 more source

Herpesvirus glycoproteins undergo multiple antigenic changes before membrane fusion. [PDF]

open access: yesPLoS ONE, 2012
Herpesvirus entry is a complicated process involving multiple virion glycoproteins and culminating in membrane fusion. Glycoprotein conformation changes are likely to play key roles.
Daniel L Glauser   +2 more
doaj   +1 more source

Glycoproteins of the lysosomal membrane. [PDF]

open access: yesThe Journal of cell biology, 1985
Three glycoprotein antigens (120, 100, and 80 kD) were detected by mono- and/or polyclonal antibodies generated by immunization with highly purified rat liver lysosomal membranes. All of the antigens were judged to be integral membrane proteins based on the binding of Triton X-114.
Ari Helenius   +5 more
openaire   +3 more sources

Glycan structures contain information for the spatial arrangement of glycoproteins in the plasma membrane. [PDF]

open access: yesPLoS ONE, 2013
Glycoconjugates at the cell surface are crucial for cells to communicate with each other and the extracellular microenvironment. While it is generally accepted that glycans are vectorial biopolymers, their information content is unclear.
M Kristen Hall   +4 more
doaj   +1 more source

Tamoxifen-resistant breast cancer cells exhibit reactivity with Wisteria floribunda agglutinin.

open access: yesPLoS ONE, 2022
Glycosylation is one of the most important post-translational modifications of cell surface proteins involved in the proliferation, metastasis and treatment resistance of cancer cells.
May Thinzar Hlaing   +11 more
doaj   +1 more source

Structures of the Hepaci-, Pegi-, and Pestiviruses envelope proteins suggest a novel membrane fusion mechanism.

open access: yesPLoS Biology, 2023
Enveloped viruses encode specialised glycoproteins that mediate fusion of viral and host membranes. Discovery and understanding of the molecular mechanisms of fusion have been achieved through structural analyses of glycoproteins from many different ...
Michael R Oliver   +5 more
doaj   +1 more source

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