Results 11 to 20 of about 2,327,252 (364)
Retinal glycoprotein enrichment by concanavalin a enabled identification of novel membrane autoantigen synaptotagmin-1 in equine recurrent uveitis. [PDF]
PLoS ONE, 2012 Complete knowledge of autoantigen spectra is crucial for understanding pathomechanisms of autoimmune diseases like equine recurrent uveitis (ERU), a spontaneous model for human autoimmune uveitis. While several ERU autoantigens were identified previously,
Margarete E Swadzba +4 more
doaj +20 more sources
Viruses, 2021 Herpes simplex virus type-1 (HSV-1) and type-2 (HSV-2) are prototypical alphaherpesviruses that are characterized by their unique properties to infect trigeminal and dorsal root ganglionic neurons, respectively, and establish life-long latent infections.
Nithya Jambunathan +5 more
doaj +1 more source
Glycoproteins of the lysosomal membrane. [PDF]
The Journal of cell biology, 1985 Three glycoprotein antigens (120, 100, and 80 kD) were detected by mono- and/or polyclonal antibodies generated by immunization with highly purified rat liver lysosomal membranes. All of the antigens were judged to be integral membrane proteins based on the binding of Triton X-114.
Ari Helenius +5 more
openaire +3 more sources
Glycan structures contain information for the spatial arrangement of glycoproteins in the plasma membrane. [PDF]
PLoS ONE, 2013 Glycoconjugates at the cell surface are crucial for cells to communicate with each other and the extracellular microenvironment. While it is generally accepted that glycans are vectorial biopolymers, their information content is unclear.
M Kristen Hall +4 more
doaj +1 more source
Tamoxifen-resistant breast cancer cells exhibit reactivity with Wisteria floribunda agglutinin.
PLoS ONE, 2022 Glycosylation is one of the most important post-translational modifications of cell surface proteins involved in the proliferation, metastasis and treatment resistance of cancer cells.
May Thinzar Hlaing +11 more
doaj +1 more source
PLoS Biology, 2023 Enveloped viruses encode specialised glycoproteins that mediate fusion of viral and host membranes. Discovery and understanding of the molecular mechanisms of fusion have been achieved through structural analyses of glycoproteins from many different ...
Michael R Oliver +5 more
doaj +1 more source
Communications Biology, 2021 Reiding et al. performed conventional proteomics as well as glycoproteomics on protein extracts from lysates of pooled neutrophils obtained from ten healthy donors.
Karli R. Reiding +4 more
doaj +1 more source
Antibody binding reports spatial heterogeneities in cell membrane organization
Nature Communications, 2023 The spatial organization of cell membrane glycoproteins and glycolipids is critical for mediating the binding of ligands, receptors, and macromolecules on the plasma membrane.
Daniel P. Arnold +2 more
doaj +1 more source
BioTechniques, 2001 Here, we describe a simple and sensitive method that allows fluorescent detection of glycoproteins on polyvinylidene difluoride (PVDF) membrane. We used periodic acid oxidation of carbohydrate chains of glycoproteins and fluorescent labeling with 8 ...
F.Y. Che +4 more
doaj +1 more source
Fusion of Sendai virus with the target cell membrane is required for T cell cytotoxicity [PDF]
, 1978 INFECTION of mice with viruses can generate cytotoxic T lymphocytes (CTL) which show restricted specificity for target cell lysis. Specific lysis requires that the virus used to prime the target cells must be of the same type as that used to sensitise ...
A Munro +12 more
core +1 more source