Results 11 to 20 of about 2,276,728 (407)

Glycoproteins of the lysosomal membrane. [PDF]

The Journal of cell biology, 1985
Three glycoprotein antigens (120, 100, and 80 kD) were detected by mono- and/or polyclonal antibodies generated by immunization with highly purified rat liver lysosomal membranes. All of the antigens were judged to be integral membrane proteins based on the binding of Triton X-114.
Ari Helenius, Mark Marsh, S A Green, Lewis, Ira Mellman, P Vihko   +5 more
openaire   +3 more sources

Glycan structures contain information for the spatial arrangement of glycoproteins in the plasma membrane. [PDF]

PLoS ONE, 2013
Glycoconjugates at the cell surface are crucial for cells to communicate with each other and the extracellular microenvironment. While it is generally accepted that glycans are vectorial biopolymers, their information content is unclear.
M Kristen Hall, Douglas A Weidner, Jian ming Chen, Christopher J Bernetski, Ruth A Schwalbe   +4 more
doaj   +1 more source

Tamoxifen-resistant breast cancer cells exhibit reactivity with Wisteria floribunda agglutinin.

PLoS ONE, 2022
Glycosylation is one of the most important post-translational modifications of cell surface proteins involved in the proliferation, metastasis and treatment resistance of cancer cells.
May Thinzar Hlaing, Yoshiya Horimoto, Kaori Denda-Nagai, Haruhiko Fujihira, Miki Noji, Hiroyuki Kaji, Azusa Tomioka, Yumiko Ishizuka, Harumi Saeki, Atsushi Arakawa, Mitsue Saito, Tatsuro Irimura   +11 more
doaj   +1 more source

Structures of the Hepaci-, Pegi-, and Pestiviruses envelope proteins suggest a novel membrane fusion mechanism.

PLoS Biology, 2023
Enveloped viruses encode specialised glycoproteins that mediate fusion of viral and host membranes. Discovery and understanding of the molecular mechanisms of fusion have been achieved through structural analyses of glycoproteins from many different ...
Michael R Oliver, Kamilla Toon, Charlotte B Lewis, Stephen Devlin, Robert J Gifford, Joe Grove   +5 more
doaj   +1 more source

Neutrophil azurophilic granule glycoproteins are distinctively decorated by atypical pauci- and phosphomannose glycans

Communications Biology, 2021
Reiding et al. performed conventional proteomics as well as glycoproteomics on protein extracts from lysates of pooled neutrophils obtained from ten healthy donors.
Karli R. Reiding, Yu-Hsien Lin, Floris P. J. van Alphen, Alexander B. Meijer, Albert J. R. Heck   +4 more
doaj   +1 more source

Fluorescent Staining of Glycoproteins on Polyvinylidene Difluoride Membrane with 8-Aminonaphthalene-1,3,6-Trisulfonate

BioTechniques, 2001
Here, we describe a simple and sensitive method that allows fluorescent detection of glycoproteins on polyvinylidene difluoride (PVDF) membrane. We used periodic acid oxidation of carbohydrate chains of glycoproteins and fluorescent labeling with 8 ...
F.Y. Che, J.F. Song, L.R. Yu, K.Y. Wang, Q.C. Xia   +4 more
doaj   +1 more source

Human galectin-1 and galectin-3 promote Tropheryma whipplei infection

Gut Microbes, 2021
Tropheryma whipplei, is an actinobacterium that causes different infections in humans, including Whipple’s disease. The bacterium infects and replicates in macrophages, leading to a Th2-biased immune response. Previous studies have shown that T. whipplei
Diyoly Ayona, Sandra Madariaga Zarza, Ludovic Landemarre, Benoît Roubinet, Philippe Decloquement, Didier Raoult, Pierre-Edouard Fournier, Benoit Desnues   +7 more
doaj   +1 more source

Host antiviral factors hijack furin to block SARS-CoV-2, ebola virus, and HIV-1 glycoproteins cleavage

Emerging Microbes and Infections, 2023
Viral envelope glycoproteins are crucial for viral infections. In the process of enveloped viruses budding and release from the producer cells, viral envelope glycoproteins are presented on the viral membrane surface as spikes, promoting the virus's next-
Changqing Yu, Guosheng Wang, Qiang Liu, Jingbo Zhai, Mengzhou Xue, Qiang Li, Yuanhua Xian, Chunfu Zheng   +7 more
doaj   +1 more source

Fusion of Sendai virus with the target cell membrane is required for T cell cytotoxicity [PDF]

, 1978
INFECTION of mice with viruses can generate cytotoxic T lymphocytes (CTL) which show restricted specificity for target cell lysis. Specific lysis requires that the virus used to prime the target cells must be of the same type as that used to sensitise ...
A Munro, A Scheid, H Tozawa, JW Schrader, K Sugamura, M Homma, MARY-JANE GETHING, MICHAEL WATERFIELD, RM Zinkernagel, U Koszinowski, U Koszinowski, ULRICH KOSZINOWSKI, Y Hosaka   +12 more
core   +1 more source

The formation of Ca++-dependent complexes of platelet membrane glycoproteins IIb and IIIa in solution as determined by crossed immunoelectrophoresis.

Blood, 1981
Triton X-100 soluble proteins from 125I-labeled human platelets were studied by crossed immunoelectrophoresis employing a multispecific rabbit antibody raised against whole normal platelets.
T. Kunicki, D. Pidard, J. Rosa, A. Nurden   +3 more
semanticscholar   +2 more sources