Results 41 to 50 of about 2,350,953 (316)

Requirements for Human Respiratory Syncytial Virus Glycoproteins in Assembly and Egress from Infected Cells

open access: yesAdvances in Virology, 2011
Human respiratory syncytial virus (HRSV) is an enveloped RNA virus that assembles and buds from the plasma membrane of infected cells. The ribonucleoprotein complex (RNP) must associate with the viral matrix protein and glycoproteins to form newly ...
Melissa Batonick, Gail W. Wertz
doaj   +1 more source

Lewis X antigen mediates adhesion of human breast carcinoma cells to activated endothelium. Possible involvement of the endothelial scavenger receptor C-Type lectin [PDF]

open access: yes, 2007
Lewis x (Lex, CD15), also known as SSEA-1 (stage specific embryonic antigen-1), is a trisaccharide with the structure Galβ(1–4)Fucα(1–3)GlcNAc, which is expressed on glycoconjugates in human polymorphonuclear granulocytes and various tumors such as colon
A Hittelet   +51 more
core   +1 more source

Dynamic organization of Herpesvirus glycoproteins on the viral envelope revealed by super-resolution microscopy.

open access: yesPLoS Pathogens, 2019
The processes of cell attachment and membrane fusion of Herpes Simplex Virus 1 involve many different envelope glycoproteins. Viral proteins gC and gD bind to cellular receptors.
Frauke Beilstein   +5 more
doaj   +1 more source

Understanding the process of envelope glycoprotein incorporation into virions in simian and feline immunodeficiency viruses [PDF]

open access: yes, 2014
The lentiviral envelope glycoproteins (Env) mediate virus entry by interacting with specific receptors present at the cell surface, thereby determining viral tropism and pathogenesis.
Affranchino, Jose Luis   +1 more
core   +4 more sources

Towards Understanding KSHV Fusion and Entry

open access: yesViruses, 2019
How viruses enter cells is of critical importance to pathogenesis in the host and for treatment strategies. Over the last several years, the herpesvirus field has made numerous and thoroughly fascinating discoveries about the entry of alpha-, beta-, and ...
Stephen J. Dollery
doaj   +1 more source

Conformational plasticity underlies membrane fusion induced by an HIV sequence juxtaposed to the lipid envelope

open access: yesScientific Reports, 2021
Envelope glycoproteins from genetically-divergent virus families comprise fusion peptides (FPs) that have been posited to insert and perturb the membranes of target cells upon activation of the virus-cell fusion reaction.
Igor de la Arada   +7 more
doaj   +1 more source

The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents [PDF]

open access: yes, 2005
Strong thrombocytopenia is observed during acute infection with Trypanosoma cruzi, the parasitic protozoan agent of American trypanosomiasis or Chagas' disease.
Campetella, O.   +4 more
core   +2 more sources

Monensin and FCCP inhibit the intracellular transport of alphavirus membrane glycoproteins

open access: yesJournal of Cell Biology, 1980
Temperature-sensitive mutants of semliki forest virus (SFV) and sindbis virus (SIN) were used to study the intracellular transport of virus membrane glycoproteins in infected chicken embryo fibroblasts.
L. Kääriäinen   +4 more
semanticscholar   +1 more source

Alterations of membrane curvature during influenza virus budding [PDF]

open access: yes, 2014
Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Agnieszka Martyna   +29 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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