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Characterization of Cell Glycocalyx with Mass Spectrometry Methods. [PDF]
, 2019 The cell membrane plays an important role in protecting the cell from its extracellular environment. As such, extensive work has been devoted to studying its structure and function.
Lebrilla, Carlito B +3 more
core +2 more sources
Membrane curvature regulates the spatial distribution of bulky glycoproteins
Nature Communications, 2022 MUC1 is a heavily glycosylated protein on the cell surface. Here the authors show that MUC1 prefers negative over positive membrane curvature due to its bulky size, enabling MUC1 to avoid endocytosis and surface removal based on curvature preference.
Chih-Hao Lu +7 more
doaj +1 more source
Fusogenic structural changes in arenavirus glycoproteins are associated with viroporin activity.
PLoS Pathogens, 2023 Many enveloped viruses enter host cells by fusing with acidic endosomes. The fusion activity of multiple viral envelope glycoproteins does not generally affect viral membrane permeability.
You Zhang +4 more
doaj +1 more source
Mechanisms of pattern formation during T cell adhesion [PDF]
, 2004 T cells form intriguing patterns during adhesion to antigen-presenting cells. The patterns at the cell-cell contact zone are composed of two types of domains, which either contain short TCR/MHCp receptor-ligand complexes or the longer LFA-1/ICAM-1 ...
Alberts +58 more
core +4 more sources
Recognition of viral glycoproteins by influenza A-specific cross- reactive cytolytic T lymphocytes [PDF]
, 1980 Two populations of cytolytic T lymphocytes (CTL) generated after influenza A virus infection can be distinguished into one with specificity for the sensitizing hemagglutinin type and a second with cross-reactivity for antigens induced by other type-A ...
Allen, H. +4 more
core +2 more sources
Identification of two lysosomal membrane glycoproteins
Journal of Cell Biology, 1985 Two murine lysosome-associated membrane proteins, LAMP-1 of 105,000- 115,000 D and LAMP-2 of 100,000-110,000 D, have been identified by monoclonal antibodies that bind specifically to lysosomal membranes. Both glycoproteins were distinguished as integral
Jeff W. Chen +4 more
semanticscholar +1 more source
Viruses, 2014 Paramyxoviruses are a family of negative sense RNA viruses whose members cause serious diseases in humans, such as measles virus, mumps virus and respiratory syncytial virus; and in animals, such as Newcastle disease virus and rinderpest virus ...
Farah El Najjar +2 more
doaj +1 more source
Follicle-stimulating hormone receptor: Advances and remaining challenges [PDF]
In: Arun K. Shukla (ed.), dir., G Protein-Coupled Receptors:
Emerging Paradigms in Activation, Signaling and Regulation Part A (p. 1-58).
International Review of Cell and Molecular Biology, 338 (1\`ere ed.). USA :
Elsevier. 171 p. (2018), 2018 Follicle-stimulating hormone (FSH) is produced in the pituitary and is essential for reproduction. It specifically binds to a membrane receptor (FSHR) expressed in somatic cells of the gonads. The FSH/FSHR system presents many peculiarities compared to classical G protein-coupled receptors (GPCRs).
arxiv +1 more source
Paranodin, a Glycoprotein of Neuronal Paranodal Membranes [PDF]
Neuron, 1997 Ranvier nodes are flanked by paranodal regions, at the level of which oligodendrocytes or Schwann cells interact closely with axons. Paranodes play a critical role in the physiological properties of myelinated nerve fibers. Paranodin, a prominent 180 kDa transmembrane neuronal glycoprotein, was purified and cloned from adult rat brain, and found to be ...
Menegoz, Mathias +8 more
openaire +4 more sources
Advances in Virology, 2011 Human respiratory syncytial virus (HRSV) is an enveloped RNA virus that assembles and buds from the plasma membrane of infected cells. The ribonucleoprotein complex (RNP) must associate with the viral matrix protein and glycoproteins to form newly ...
Melissa Batonick, Gail W. Wertz
doaj +1 more source