Results 51 to 60 of about 133,090 (338)
Protein Geometry, Function and Mutation [PDF]
arXiv, 2022 This survey for mathematicians summarizes several works by the author on protein geometry and protein function with applications to viral glycoproteins in general and the spike glycoprotein of the SARS-CoV-2 virus in particular. Background biology and biophysics are sketched.
arxiv
Paramyxovirus Glycoproteins and the Membrane Fusion Process [PDF]
Current Clinical Microbiology Reports, 2016 The family Paramyxoviridae includes many viruses that significantly affect human and animal health. An essential step in the paramyxovirus life cycle is viral entry into host cells, mediated by virus-cell membrane fusion. Upon viral entry, infection results in expression of the paramyxoviral glycoproteins on the infected cell surface.
J Lizbeth Reyes Zamora +3 more
openaire +3 more sources
FEBS Letters, Volume 599, Issue 7, Page 1055-1074, April 2025.Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard +7 more
wiley +1 more source
Unwrapping the Ciliary Coat: High‐Resolution Structure and Function of the Ciliary Glycocalyx
Advanced ScienceThe glycocalyx, a highly heterogeneous glycoprotein layer of cilia regulates adhesion and force transduction and is involved in signaling. The high‐resolution molecular architecture of this layer is currently not understood.
Lara M. Hoepfner +8 more
doaj +1 more source
Mathematical modeling to elucidate brain tumor abrogation by immunotherapy with T11 target structure [PDF]
, 2014 T11 Target structure (T11TS), a membrane glycoprotein isolated from sheep erythrocytes, reverses the immune suppressed state of brain tumor induced animals by boosting the functional status of the immune cells. This study aims at aiding in the design of more efficacious brain tumor therapies with T11 target structure.
arxiv +1 more source
The Coronavirus Membrane Glycoprotein [PDF]
, 1995 Coronaviruses have a simple protein composition. While there is some variation among different members, a basic set of four protein species universally occurs: the nucleocapsid protein (N), the spike protein (S), a small membrane protein (SM), and the membrane glycoprotein (M). Some coronaviruses have an additional membrane glycoprotein (HE).
openaire +2 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
E-Journal of Chemistry, 2009 The present study was undertaken to examine the inhibitory effect of crude leaves of Dodonaea viscosa (L) on lead acetate induced synthesis of glycoproteins and sialic acid in liver and plasma.
D. Sivanesan +3 more
doaj +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Breaking In: Human Metapneumovirus Fusion and Entry
Viruses, 2013 Human metapneumovirus (HMPV) is a leading cause of respiratory infection that causes upper airway and severe lower respiratory tract infections. HMPV infection is initiated by viral surface glycoproteins that attach to cellular receptors and mediate ...
John V. Williams, Reagan G. Cox
doaj +1 more source