Results 281 to 290 of about 14,870,238 (380)

The involvements of intracellular basal calcium and membrane potential in para-phenylenediamine-impaired sperm function. [PDF]

Transl Androl Urol
Chen Y, Yang T, Gu X, Chen Y, Wang Q, Wang X.   +5 more
europepmc   +1 more source

Bcl-xL Regulates the Membrane Potential and Volume Homeostasis of Mitochondria

Cell, 1997
M. V. Heiden, N. Chandel, E. Williamson, P. Schumacker, C. Thompson   +4 more
semanticscholar   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Veratridine-Induced Oscillations in Nav 1.7 but Not Nav 1.5 Sodium Channels Are Revealed by Membrane Potential Sensitive Dye. [PDF]

Membranes (Basel)
Lummis SCR, Salvage SC, Huang CL, Jackson AP.   +3 more
europepmc   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Mechanisms of <i>mepA</i> Overexpression and Membrane Potential Reduction Leading to Ciprofloxacin Heteroresistance in a <i>Staphylococcus aureus</i> Isolate. [PDF]

Int J Mol Sci
Li M, Jian Q, Ye X, Jing M, Wu J, Wu Z, Ruan Y, Long X, Zhang R, Ren H, Sun J, Liu Y, Liao X, Lian X.   +13 more
europepmc   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

Osmotic pressure‐induced calcium response states

FEBS Open Bio, EarlyView.
Acute hypotonic stress triggers distinct calcium response patterns in HEK293T cells. These signals originate from the endoplasmic reticulum via RyR2 and propagate to neighboring cells through gap junctions. This result highlights a novel calcium‐dependent mechanism underlying the intracellular and intercellular response to osmotic pressure.
Zidan Gao, Keiji Naruse, Masatoshi Morimatsu   +2 more
wiley   +1 more source

Membrane potential mediates the cellular binding of nanoparticles.

Nanoscale, 2013
Edwin H Shin, Ye Li, Umesh Kumar, Hursh V. Sureka, Xianren Zhang, C. Payne   +5 more
semanticscholar   +1 more source

Computed Action Potentials for Purkinje Fiber Membranes with Resistance and Capacitance in Series

, 1968
R. E. McAllister
openalex   +1 more source