Results 81 to 90 of about 511,878 (297)

Nanodiamond Sensing in Dynamic Environments With Fast‐Tracking Through Four‐Point Positioning

Advanced Functional Materials, EarlyView.
A four‐point positioning tracking (4PPT) platform enables fast 3D feedback translational tracking of fluorescent nanodiamonds while simultaneously recording ODMR spectra. By integrating real‐time translational tracking with quantum sensing, mobile nanodiamonds are used for in‐situ nanothermometry, nanorheometry, and 6D translation–rotation tracking in ...
Guoli Zhu, Ming‐Zhong Ai, Zhi‐Yu Zhao, Weng‐Hang Leong, Shi‐Ning Chen, Xi Liu, Jing‐Wei Fan, Xi Feng, Ren‐Bao Liu, Yue Cui, Quan Li   +10 more
wiley   +1 more source

Frequency of subthreshold oscillations at different membrane potential voltages in neurons at different anatomical positions on the dorso-ventral axis in the rat medial entorhinal cortex

Journal of Neuroscience, 2011
Neurons from layer II of the medial entorhinal cortex show subthreshold membrane potential oscillations (SMPOs) which could contribute to theta-rhythm generation in the entorhinal cortex and to generation of grid cell firing patterns.
Motoharu Yoshida, Lisa M. Giocomo, I. Boardman, M. Hasselmo   +3 more
semanticscholar   +1 more source

A 3D Human Neuron‐on‐Chip Platform to Monitor Neuronal Injury Responses

Advanced Healthcare Materials, EarlyView.
This study presents a novel 3D Neuron‐on‐Chip model that can maintain human PSC‐derived excitatory prefrontal cortex neurons in 3D hydrogels and can be used to monitor neuronal injury responses over time. Results show injury‐induced acute neuronal excitotoxicity, declining neuronal connectivity, and the activation of a neurodegenerative, SASP‐like ...
Ruiping Tang, Charles‐Francois Latchoumane, Avi Chopra, Md Marzan Sarkar, Chunki Kim, Nathan Gonsalves, Hsueh‐Fu Wu, John C. Sentmanat, Alan Liu, Isha Mhatre‐Winters, Aditya Mishra, Andrei G. Fedorov, Jay M. Patel, Nadja Zeltner, Steven L. Stice, Jason R. Richardson, Lohitash Karumbaiah   +16 more
wiley   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Neuronal synchronization in Drosophila

iScience
Summary: Collective rhythms are intrinsic to biological processes across temporal and spatial scales. In the brain, synchronized neuronal oscillations underlie collective rhythms essential for complex functions.
Florencia Fernandez-Chiappe, Marcos Wappner, Luis G. Morelli, Nara I. Muraro   +3 more
doaj   +1 more source

Calcium-Mediated Oscillation in Membrane Potentials and Atrial-Triggered Activity in Atrial Cells of Casq2R33Q/R33Q Mutation Mice

Frontiers in Physiology, 2018
Aim: We investigated the underlying mechanisms in atrial fibrillation (AF) associated with R33Q mutation and Ca2+-triggered activity.Methods and Results: We examined AF susceptibility with intraesophageal burst pacing in the sarcoplasmic reticulum (SR ...
Jian-cheng Zhang, Hong-lin Wu, Qian Chen, Xiao-ting Xie, Tian Zou, Chao Zhu, Ying Dong, Guo-jian Xiang, Lei Ye, Yang Li, Peng-li Zhu   +10 more
doaj   +1 more source

The membrane potential waveform of bursting pacemaker neurons is a predictor of their preferred frequency and the network cycle frequency

Journal of Neuroscience, 2010
Many oscillatory networks involve neurons that exhibit intrinsic rhythmicity but possess a large variety of voltage-gated currents that interact in a complex fashion, making it difficult to determine which factors control frequency.
Hua-an Tseng, F. Nadim
semanticscholar   +1 more source

Bioprinting High‐Cell‐Density Cardiac Tissue Constructs With Sustained Contractile Function

Advanced Healthcare Materials, EarlyView.
Contractile cardiomyocytes in 3D culture provide insights into the behavior of the heart. Combining a 3D bioprinting approach with a multi‐electrode array allows the development of the 3D culture to be monitored over time, and matured cultures allow the effect of drugs on cardiac function to be modelled, replicating effects seen in clinical application.
Priscila Melo, Wing Tai Tung, Harvey Lewis, Kavin Hettiarachchilage, Babis Tzivelekis, Rolando Berlinguer‐Palmini, Ana Marina Ferreira, Jason Gill, Kenneth Dalgarno   +8 more
wiley   +1 more source

Grid cell firing may arise from interference of theta frequency membrane potential oscillations in single neurons

Hippocampus, 2007
Intracellular recording and computational modelling suggest that interactions of subthreshold membrane potential oscillation frequency in different dendritic branches of entorhinal cortex stellate cells could underlie the functional coding of continuous ...
M. Hasselmo, Lisa M. Giocomo, Eric A. Zilli   +2 more
semanticscholar   +1 more source

Multifunctional Catechol‐Functionalized Cellulose Hydrogels for the Minimally Invasive Treatment of Acute Optic Nerve Injuries

Advanced Healthcare Materials, EarlyView.
Catechol‐functionalized cellulose hydrogels are developed as injectable, bioadhesive platforms for retinal neuroprotection. The hydrogels exhibit tunable rheological and mechanical properties, strong tissue adhesion, and sustained antioxidative activity.
Kai‐Hsiang Chang, Yi‐Ke Lin, Wei‐Li Chen, Ta‐Ching Chen, Jiashing Yu   +4 more
wiley   +1 more source