Results 211 to 220 of about 228,598 (287)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Sarcolemmal and mitochondrial membrane potentials measuredex vivoandin vivoin the heart by pharmacokinetic modelling of [^99mTc]sestamibi

Waters EC, Baark F, Orton MR, Shattock MJ, Southworth R, Eykyn TR.   +5 more
europepmc   +1 more source

Differential Autoregulation of Serotonin Secretion at Different Structures of Serotonergic Neurons. [PDF]

Int J Mol Sci
Trueta C, Cercós MG.
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Role of Water Models in Simulations of Ion Conduction in Potassium Channels. [PDF]

J Chem Theory Comput
Bosio S, Gazzoni D, Domene C, Masetti M, Furini S.   +4 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Cold Shock Compromises the Electrically Mediated Block to Polyspermy in Lytechinus variegatus Eggs. [PDF]

Mol Reprod Dev
Ivonnet PI, Chambers L, Künzi L, Garcia G.   +3 more
europepmc   +1 more source

Effects of Bitter Antibiotics on Electrical Potential Oscillation across a Water/Octanol/Water Liquid Membrane

, 1999
Kensuke Arai, Kakujirou Watanabe, Fumiyo Kusu   +2 more
openalex   +2 more sources

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Flicker-Suppressed Neuromorphic Unit for Dynamic Vision Processing. [PDF]

ACS Nano
Xie P, Shi S, Ran L, Wang C, Li D, Zhang Y, Wei Y, Quan Q, Li B, Meng Y, Wang W, Gao B, Lan C, Leung MKH, Wang Z, Ho JC.   +15 more
europepmc   +1 more source