Results 231 to 240 of about 438,564 (323)

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Predicting neural responses to intra- and extra-cranial electric brain stimulation by means of the reciprocity theorem. [PDF]

PLoS Comput Biol
Ness TV, Koch C, Einevoll GT.
europepmc   +1 more source

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

FEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita, Toyonobu Usuki, Robert R. Kay, Tamao Saito   +3 more
wiley   +1 more source

Role of BK channels and Kv4.2 channels in the electrophysiological properties of Merkel cells in rat whisker hair follicles. [PDF]

J Neurophysiol
Yamada A, Gu J.
europepmc   +1 more source

Exogenous Carbon Monoxide Prevents a Decrease of Mitochondrial Membrane Potential in Lipopolysaccharide-Stimulated Platelets

Tomiko Yakura, Eri Nanizawa, Yutaro Natuyama, Shinichi Kawata, Miyuki Kuramasu, Zhong‐Lian Li, Hidenobu Miyaso, Munekazu Naito, Masahiro Itoh   +8 more
openalex   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Subarachnoid hemorrhage mediates human neocortical network, membrane potential, and action potential bursting via glutamate receptors. [PDF]

Commun Biol
Huang DF, Chou MY, Lee YH, Chen YT, Sun CK, Wang KC, Huang HS.   +6 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Relaxed Boundary Conditions in Poisson-Nernst-Planck Models: Identifying Critical Potentials for Multiple Cations. [PDF]

Membranes (Basel)
Liu X, Ndaya H, Nguyen A, Wen Z, Zhang M.   +4 more
europepmc   +1 more source

Functional Implications of Synaptic Spike Timing Dependent Plasticity and Anti-Hebbian Membrane Potential Dependent Plasticity

, 2015
Christian Albers
openalex   +1 more source