Results 71 to 80 of about 442,263 (324)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Accelerating compartmental modeling on a graphical processing unit

Frontiers in Neuroinformatics, 2013
Compartmental modeling is a widely used tool in neurophysiology but the detail and scope of such models is frequently limited by lack of computational resources. Here we implement compartmental modeling on low cost Graphical Processing Units (GPUs).
Roy eBen-Shalom, Roy eBen-Shalom, Gilad eLiberman, Alon eKorngreen, Alon eKorngreen   +4 more
doaj   +1 more source

Striatal cholinergic interneuron membrane voltage tracks locomotor rhythms in mice

Nature Communications, 2023
Rhythmic neural network activity has been broadly linked to behavior. However, it is unclear how membrane potentials of individual neurons track behavioral rhythms, even though many neurons exhibit pace-making properties in isolated brain circuits.
Sanaya N. Shroff, Eric Lowet, Sudiksha Sridhar, Howard J. Gritton, Mohammed Abumuaileq, Hua-An Tseng, Cyrus Cheung, Samuel L. Zhou, Krishnakanth Kondabolu, Xue Han   +9 more
doaj   +1 more source

Single-channel recordings from cultured human retinal pigment epithelial cells. [PDF]

, 1988
We have applied patch-clamp techniques to on-cell and excised-membrane patches from human retinal pigment epithelial cells in tissue culture. Single-channel currents from at least four ion channel types were observed: three or more potassium-selective ...
Fain, GL, Fox, JA, Pfeffer, BA
core  

Characterization of Shewanella oneidensis MtrC: a cell-surface decaheme cytochrome involved in respiratory electron transport to extracellular electron acceptors [PDF]

, 2007
MtrC is a decaheme c-type cytochrome associated with the outer cell membrane of Fe(III)-respiring species of the Shewanella genus. It is proposed to play a role in anaerobic respiration by mediating electron transfer to extracellular mineral oxides that ...
AI Tsapin, AJ Bard, AS Beliaev, AS Beliaev, BH Kim, Brian N. Jepson, C Myers, C Myers, C Schwalb, CR Myers, CR Myers, CR Myers, CR Myers, D Leys, David J. Richardson, DJ Richardson, E Berry, EHJ Gordon, FA Walker, GR Moore, HJ Kim, I Gautier-Luneau, J Hirst, JF Heidelberg, Jim Fredrickson, JK Fredrickson, JM Myers, JM Myers, JM Philo, John Zachara, Julea N. Butt, K Venkateswaren, KE Pitts, KH Nealson, KH Nealson, Kurnikov, L Shi, L Shi, Liang Shi, LJ Anderson, MG Almeida, MP Hendrich, MP Hendrich, PL Dutton, PS Dobbin, R Aasa, Robert S. Hartshorne, Sarah J. Field, SJ Field, T Horan, TA Clarke, Tom A. Clarke, VA Bamford   +52 more
core   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Movement of ions across membranes: an active learning resource

Advances in Physiology Education
This paper describes a short ion flow activity that can be completed within one lab or lecture session. The activity is focused on the core concept of flow-down gradients and is geared toward undergraduates.
J. E. Hall, L. A. Pleasant, M. D. Kinkel
doaj   +1 more source

A Quantum-mechanical description of ion motion within the confining potentials of voltage gated ion channels

, 2012
Voltage gated channel proteins cooperate in the transmission of membrane potentials between nerve cells. With the recent progress in atomic-scaled biological chemistry it has now become established that these channel proteins provide highly correlated ...
Bernroider G., Bernroider G., Briegel H. J., Corry B., Gustav Bernroider, Johann Summhammer, Thomas J. W., Vahid Salari   +7 more
core   +2 more sources

Onsager’s variational principle in soft matter : introduction and application to the dynamics of adsorption of proteins onto fluid membranes [PDF]

, 2018
This book is the first collection of lipid-membrane research conducted by leading mechanicians and experts in continuum mechanics. It brings the overall intellectual framework afforded by modern continuum mechanics to bear on a host of challenging ...
Arroyo Balaguer, Marino, Kaurin, Dimitri Jean Antoine, Torres Sánchez, Alejandro, Walani, Nikhil   +3 more
core   +2 more sources