Results 71 to 80 of about 12,112,951 (393)

Solvent-free coarse-grained lipid model for large-scale simulations

open access: yes, 2010
A coarse-grained molecular model, which consists of a spherical particle and an orientation vector, is proposed to simulate lipid membrane on a large length scale.
Allen M. P.   +6 more
core   +1 more source

Synaptic Interactions between Primate Precentral Cortex Neurons Revealed by Spike-Triggered Averaging of Intracellular Membrane Potentials In Vivo

open access: yesJournal of Neuroscience, 1996
To document synaptic interactions between neurons in the precentral cortex of macaque monkeys, we recorded in vivo the intracellular (IC) membrane potentials of cortical neurons simultaneously with extracellular (EC) action potentials of neighboring ...
M. Matsumura   +4 more
semanticscholar   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Accelerating compartmental modeling on a graphical processing unit

open access: yesFrontiers in Neuroinformatics, 2013
Compartmental modeling is a widely used tool in neurophysiology but the detail and scope of such models is frequently limited by lack of computational resources. Here we implement compartmental modeling on low cost Graphical Processing Units (GPUs).
Roy eBen-Shalom   +4 more
doaj   +1 more source

The Dynamic Role of Breathing and Cellular Membrane Potentials in the Experience of Consciousness [PDF]

open access: yes, 2017
Understanding the mechanics of consciousness remains one of the most important challenges in modern cognitive science. One key step toward understanding consciousness is to associate unconscious physiological processes with subjective experiences of ...
Barnes, Vernon A.   +3 more
core   +1 more source

Dependence of serosal membrane potential on mucosal membrane potential in toad urinary bladder

open access: yesBiophysical Journal, 1975
Ussing's model for sodium transport across epithelia assumes the existence of two barriers in series; the outer barrier behaves as a sodium electrode and the inner barrier as a potassium electrode (Koefoed-Johnsen and Ussing, 1958); furthermore, these membranes are supposed to be independent of one another.
A.L. Finn, L. Reuss
openaire   +3 more sources

Cardiac calcium channels in planar lipid bilayers. L-type channels and calcium-permeable channels open at negative membrane potentials

open access: yesThe Journal of General Physiology, 1988
Planar lipid bilayer recordings were used to study Ca channels from bovine cardiac sarcolemmal membranes. Ca channel activity was recorded in the absence of nucleotides or soluble enzymes, over a range of membrane potentials and ionic conditions that ...
Robert L. Rosenberg   +2 more
semanticscholar   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Effects of beauvericin on root cell transmembrane electric potential, electrolyte leakage and respiration of maize roots with different susceptibility to Fusarium

open access: yesPlant, Soil and Environment, 2006
Effect of beauvericin on root cell transmembrane electric potential (EM), electrolyte leakage and respiration of roots were studied in two maize cultivars (Zea mays L.) with different susceptibility to this toxigenic metabolite produced by Fusarium ...
J. Pavlovkin   +3 more
doaj   +1 more source

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