Results 91 to 100 of about 220,443 (295)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Objectives: According to Tibetan-Mongolian traditional medicine theory, humans are classified into three main individuals based on the Rlung, Mkhris or Badgan symbolic code (SC).
Narantsetseg Badarch +3 more
doaj +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Studies on the membrane potentials of some imperfect clay and shale membranes
The membrane potentials of three imperfect shale membranes were measured for a number of electrolytes. The transference numbers of ions within the membranes were determined in an apparatus which is described.
Williams, Sherrod Ambrose
core
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Correlations of the free membrane potentials of stimulated MSNs in the striatum network.
(A) Example of the free membrane potential traces of two stimulated MSNs without any input correlation ( = 0, = 0). As there was no correlation, neither within nor between the inputs to the two MSNs, the free membrane potentials did not show any ...
Man Yi Yim (339030) +2 more
core +1 more source
Shengmaisan Regulates Pacemaker Potentials in Interstitial Cells of Cajal in Mice
Objectives: Shengmaisan (SMS) is a traditional Chinese medicine prescription widely used for the treatment of diverse organs in Korea. The interstitial cells of Cajal (ICCs) are pacemaker cells that play an important role in the generation of coordinated
Kim Byung Joo
doaj +1 more source
Potassium ion current in nerve membrane, IK, has traditionally been described by IK = gK(V-EK), where gK is the K ion conductance, V is membrane potential, and EK is the K+ Nernst potential. This description has been unchallenged by most investigators in
john r Clay
doaj +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Effects of calcium deficiency on cell membrane potentials of isolated frog hearts
Membrane potentials were recorded in isolated frog hearts. Observations were made on the effects of calcium deficiency upon resting potential, action potential, overshoot, maximum depolarization rate and action potential contour.
F. Ware, A. L. Bennett, A. R. McIntyre
core +1 more source

