Results 71 to 80 of about 1,708,376 (302)
Optogenetic monitoring of membrane potentials [PDF]
Experimental Physiology, 2010 Over the last decade, researchers in our laboratory have engineered and developed several series of genetically encoded voltage‐sensitive fluorescent proteins (VSFPs) by molecular fusion of a voltage‐sensing domain operand with different fluorescent reporter proteins.
Hiroki, Mutoh +4 more
openaire +2 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Non-linear population firing rates and voltage sensitive dye signals in visual areas 17 and 18 to short duration stimuli. [PDF]
PLoS ONE, 2008 Visual stimuli of short duration seem to persist longer after the stimulus offset than stimuli of longer duration. This visual persistence must have a physiological explanation.
David Eriksson +2 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Effect of humic-acid fouling on membrane distillation
, 2016 Membrane distillation (MD) can concentrate non-volatile solutes or remove volatiles and dissolved gases from an aqueous feed. A microporous hydrophobic membrane provides a barrier between the hot feed and cold distillate.
Tan, Yong Zen +2 more
core +1 more source
Movement of ions across membranes: an active learning resource
Advances in Physiology EducationThis paper describes a short ion flow activity that can be completed within one lab or lecture session. The activity is focused on the core concept of flow-down gradients and is geared toward undergraduates.
J. E. Hall, L. A. Pleasant, M. D. Kinkel
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
, 2018 Porous hydrophobic polyvinylidene fluoride (PVDF) membranes have been extensively used in direct-contact membrane distillation (DCMD) processes. However, these PVDF membranes are vulnerable to membrane fouling and pore wetting in low surface tension ...
Chandresh Malde +7 more
core +1 more source
Accelerating compartmental modeling on a graphical processing unit
Frontiers in Neuroinformatics, 2013 Compartmental modeling is a widely used tool in neurophysiology but the detail and scope of such models is frequently limited by lack of computational resources. Here we implement compartmental modeling on low cost Graphical Processing Units (GPUs).
Roy eBen-Shalom +4 more
doaj +1 more source