Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
ON THE DETERMINATION OF ELASTIC POTENTIAL OF SPHERICAL RUBBER MEMBRANES
Structural Mechanics of Engineering Constructions and Buildings, 2012 If one wants to make strength analysis of rubber membrane having large deformation, he must know the elastic potential. Having used potentials of Mooney and K.F.
N K Galimov +2 more
doaj
Photolipid excitation triggers depolarizing optocapacitive currents and action potentials
Nature CommunicationsOptically-induced changes in membrane capacitance may regulate neuronal activity without requiring genetic modifications. Previously, they mainly relied on sudden temperature jumps due to light absorption by membrane-associated nanomaterials or water ...
Carlos A. Z. Bassetto +6 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Efficient Surface Reconstruction From Noisy Data Using Regularized Membrane Potentials [PDF]
, 2009 A physically motivated method for surface reconstruction is proposed that can recover smooth surfaces from noisy and sparse data sets. No orientation information is required.
Roerdink, JBTM +8 more
core +1 more source
Theta oscillations represent collective dynamics of multineuronal membrane potentials of murine hippocampal pyramidal cells. [PDF]
Commun Biol, 2023 Noguchi A +3 more
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Membrane potentials, liquid junction potentials and transference numbers
, 1987 Membrane potentials and liq. junction potentials are discussed in terms of the ''signed'' and ''unsigned'' definitions of species transference nos. taking the resp. solvent-transfer contributions into due account.
P.R. Mussini, S. Rondinini, P. Longhi
core
Membrane potentials in K-deficient muscle
, 1963 Thirteen K-deficient and 14 pair-weighed control rats have been studied after 2 weeks on the experimental diets. Resting membrane potentials of skeletal muscle were measured immediately before killing the rats for plasma and muscle analysis.
Nick Sperlakis, Robert E. Eckel
core +1 more source