Results 121 to 130 of about 220,443 (295)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
, 2011 Adenine nucleotide translocator (ANT) 2 shRNA regulated the levels of Bcl-2 family members and disrupted mitochondrial membrane potentials to induce apoptosis in MDA-MB-231 cells. DNA laddering assay: cells were transfected with ANT2 shRNA-1, and then 48
Yoon-Kyung Jeon (47191) +3 more
core +1 more source
, 2020 The majority of chronic infections are caused by biofilms, which have higher levels of antibiotic resistance than planktonic growth. Violet-blue 405 nm light has recently emerged as a novel bactericide, but limited studies have been conducted on its ...
Waigh, T. A. +2 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The Membrane Potentials of Periderm and Cuticular Membranes
, 2002 The membrane potentials of periderm and cuticular membranes were measured with KCl and NaCl solution using Ag/AgCI electrodes. For the electromotive force (emf) measurements, the concentration in both compartments were brought to equilibrium with the 0 ...
Çengeloğlu, Yunus +2 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Stable membrane potentials and mechanical K+ responses activated by internal Ca2+ in HeLa cells
, 1983 Stable membrane potentials have been measured with microelectrodes in HeLa cells and their average value (−38 mV) compares well with the Cl− electrochemical potential (−34 mV).
G. Roy, R. Sauvé
core +1 more source
Effect of Moxibustion on Mitochondrial Membrane Potentials and Neuronal Apoptosis in Aged Rats
针刺研究, 2005 Objective: To observe changes of mitochondrial membrane potential and neuronal apoptosis and the effect of moxibustion on them in aged rats.Methods: According to the age(months),45 Wistar rats were evenly divided into young(2-3 m) group,aged(15 m) group ...
DU Yan-jun, SUN Guo-jie
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