Results 91 to 100 of about 3,087,877 (362)

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Basement membrane proteins

Kidney International, 1992
Basement membranes are heterogeneous, highly specialized, electron-dense structures constructed from components of extracellular matrix proteins 20 to 200nm in width. They provide anchorage for adjacent cells as well as stimuli for cell differentiation, cell migration, and cell phenotype.
openaire   +3 more sources

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Electrostatic forces on charged surfaces of bilayer lipid membranes [PDF]

, 2013
Simulating protein-membrane interactions is an important and dynamic area of research. A proper definition of electrostatic forces on membrane surfaces is necessary for developing electromechanical models of protein-membrane interactions. Here we modeled
Mikucki, Michael, Zhou, Y. C.
core  

Membrane-protein interactions in mechanosensitive channels [PDF]

, 2004
In this paper, we examine the mechanical role of the lipid bilayer in ion channel conformation and function with specific reference to the case of the mechanosensitive channel of large conductance (MscL).
Bass, Betanzos, Bilston, Blount, Boal, Canham, Cantor, Cantor, Chang, Chen, Dan, Dan, Dan, Dan, de Kruijff, de Kruijff, East, Elmore, Evans, Fournier, Gillespie, Goulian, Gruner, Gullingsrud, Gullingsrud, Gullingsrud, Hamill, Helfrich, Helfrich, Huang, Israelachvili, Keller, Kumar, Landau, Lundbæk, Lundbæk, Markin, Mouritsen, Mouritsen, Nielsen, Olbrich, Opsahl, O’Keeffe, Paul Wiggins, Perozo, Perozo, Polchinski, Powl, Rawicz, Rob Phillips, Sukharev, Sukharev, White, Wiggins, Yoshimura, Yoshimura   +55 more
core   +4 more sources

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Reconstitution of the Melibiose Permease of Salmonella enterica serovar Typhimurium (MelBSt) into Lipid Nanodiscs

Bio-Protocol
Membrane proteins play critical roles in cell physiology and pathology. The conventional way to study membrane proteins at protein levels is to use optimal detergents to extract proteins from membranes. Identification of the optimal detergent is tedious,
Parameswaran Hariharan, Lan Guan
doaj   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

The beta subunit of the signal recognition particle receptor is a transmembrane GTPase that anchors the alpha subunit, a peripheral membrane GTPase, to the endoplasmic reticulum membrane. [PDF]

, 1995
The signal recognition particle receptor (SR) is required for the cotranslational targeting of both secretory and membrane proteins to the endoplasmic reticulum (ER) membrane.
Lauffer, L, Miller, JD, Tajima, S, Walter, P   +3 more
core  

Natural channel protein inserts and functions in a completely artificial, solid-supported bilayer membrane [PDF]

, 2013
Reconstitution of membrane proteins in artificial membrane systems creates a platform for exploring their potential for pharmacological or biotechnological applications.
Fu, Wangyang, Meier, Wolfgang, Palivan, Cornelia G., Zhang, Xiaoyan   +3 more
core   +1 more source