Results 141 to 150 of about 2,347,830 (319)

Burkholderia collagen-like protein 8, Bucl8, is a unique outer membrane component of a putative tetrapartite efflux pump in Burkholderia pseudomallei and Burkholderia mallei

, 2020
Megan E. Grund, Soo Jeon Choi, Dudley H. McNitt, Mariette Barbier, Gangqing Hu, P. Rocco LaSala, Christopher K. Cote, Rita Berisio, Sławomir Łukomski   +8 more
openalex   +2 more sources

Real-Time Binding Kinetics of Membrane Protein-Protein Interactions in a Membraneless Setting. [PDF]

Anal Chem
Wang Y, Wu Y, Mayse LA, Capucilli D, Huang PJ, Ramachandran S, Luikham S, Ha JH, Loh SN, Wolfe AJ, Movileanu L.   +10 more
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Separation and purification of the bovine milk fat globule membrane protein and its effect on improvement of C₂C₁₂mouse skeletal muscle cell proliferation

, 2017
He Li, Weili Xu, Ying Ma, Shaobo Zhou
openalex   +2 more sources

Influenza M2 Proton Channel Activity Selectively Inhibits Trans-Golgi Network Release of Apical Membrane and Secreted Proteins in Polarized Madin-Darby Canine Kidney Cells [PDF]

, 2000
Jennifer R. Henkel, Gregory A. Gibson, Paul A. Poland, Mark Ellis, Rebecca P. Hughey, Ora A. Weisz   +5 more
openalex   +1 more source

A new paradigm for outer membrane protein biogenesis in the Bacteroidota. [PDF]

Nature
Liu X, Orenday Tapia L, Deme JC, Lea SM, Berks BC.   +4 more
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

c-Myc Represses Transcription of the Epstein-Barr Virus Latent Membrane Protein 1 Early After Primary B Cell Infection [PDF]

, 2017
Alexander M. Price, Joshua E. Messinger, Micah A. Luftig   +2 more
openalex   +1 more source

Optimizing a coarse-grained model for large-scale membrane protein simulation. [PDF]

Biophys Rep (N Y)
Wen CY, Luo YL, Madsen JJ.
europepmc   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source