Results 11 to 20 of about 3,545,588 (360)

DOCKGROUND Membrane Protein-Protein Set [PDF]

open access: yesPLOS ONE, 2021
ABSTRACTMembrane proteins play essential role in cellular mechanisms. Despite that and the major progress in experimental structure determination, they are still significantly underrepresented in Protein Data Bank. Thus, computational approaches to protein structure determination, which are important in general, are especially valuable in the case of ...
Ian Kotthoff   +2 more
openaire   +4 more sources

Sites of Biosynthesis of Outer and Inner Membrane Proteins of Neurospora crassa Mitochondria [PDF]

open access: yes, 1970
Outer and inner membranes of Neurospora crassa mitochondria were separated by the combined swelling, shrinking, sonication procedure. Membranes were characterized by electron microscopy and by marker enzyme activities.
Aasen A. J.   +14 more
core   +1 more source

A saposin-lipoprotein nanoparticle system for membrane proteins. [PDF]

open access: yes, 2016
A limiting factor in membrane protein research is the ability to solubilize and stabilize such proteins. Detergents are used most often for solubilizing membrane proteins, but they are associated with protein instability and poor compatibility with ...
Armache, Jean-Paul   +13 more
core   +2 more sources

Modular detergents tailor the purification and structural analysis of membrane proteins including G-protein coupled receptors [PDF]

open access: yes, 2020
Detergents enable the purification of membrane proteins and are indispensable reagents instructural biology. Even though a large variety of detergents have been developed in the lastcentury, the challenge remains to identify guidelines that allowfine ...
Almeida, F.   +12 more
core   +2 more sources

Intercalated Cells: More than pH Regulation

open access: yesDiseases, 2014
The renal collecting duct is the nephron segment where the final urine content of acid equivalents and inorganic ions are determined. The role of two different cell types present in this nephron segment has been determined many years ago: principal cells
Ensaf Y. Almomani   +3 more
doaj   +1 more source

Electrophysiological characterization of a diverse group of sugar transporters from Trichoderma reesei

open access: yesScientific Reports, 2021
Trichoderma reesei is an ascomycete fungus known for its capability to secrete high amounts of extracellular cellulose- and hemicellulose-degrading enzymes. These enzymes are utilized in the production of second-generation biofuels and T.
Sami Havukainen   +5 more
doaj   +1 more source

Detection of protein concentrations using a pH-step titration method [PDF]

open access: yes, 1997
A stimulus-response method based on the application of a pH step is proposed for the detection of protein immobilized in a membrane on top of an ion-sensitive field-effect transistor (ISFET). The ISFET response to a step-wise change in pH, applied at the
Bergveld, P., Eijkel, J.C.T., Kruise, J.
core   +3 more sources

X-ray crystallography reveals molecular recognition mechanism for sugar binding in a melibiose transporter MelB

open access: yesCommunications Biology, 2021
Guan and Hariharan report two crystal structures of melibiose transporter MelB in complex with substrate analogs, nitrophenyl-galactoside, and dodecyl-melibioside.
Lan Guan, Parameswaran Hariharan
doaj   +1 more source

Lipid environment determines the drug-stimulated ATPase activity of P-glycoprotein

open access: yesFrontiers in Molecular Biosciences, 2023
P-glycoprotein (Pgp) is a multidrug transporter that uses the energy from ATP binding and hydrolysis to export from cells a wide variety of hydrophobic compounds including anticancer drugs, and mediates the bioavailability and pharmacokinetics of many ...
Nghi N. B. Tran   +10 more
doaj   +1 more source

Rampant exchange of the structure and function of extramembrane domains between membrane and water soluble proteins. [PDF]

open access: yes, 2013
Of the membrane proteins of known structure, we found that a remarkable 67% of the water soluble domains are structurally similar to water soluble proteins of known structure. Moreover, 41% of known water soluble protein structures share a domain with an
Bowie, James U   +3 more
core   +3 more sources

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