Results 21 to 30 of about 6,618,097 (286)

Peroxisomal membrane proteins insert into the endoplasmic reticulum [PDF]

, 2010
We show that a comprehensive set of 16 peroxisomal membrane proteins (PMPs) encompassing all types of membrane topologies first target to the endoplasmic reticulum (ER) in Saccharomyces cerevisiae.
Sub Cellular Protein Chemistry, van der Zand, A., Tabak, H.F., Braakman, L.J., Cellular Protein Chemistry   +4 more
core   +1 more source

Protein-induced modulation of chloroplast membrane morphology [PDF]

, 2012
Organelles are surrounded by membranes with a distinct lipid and protein composition. While it is well established that lipids affect protein functioning and vice versa, it has been only recently suggested that elevated membrane protein concentrations ...
Maik S Sommer, Enrico eSchleiff, Machettira, Anu Bheemaiah, Anu B. Machettira, Englich, Gisela, Anu B Machettira, Benjamin LM Weis, Lucia E. Groß, Giesela eEnglich, Enrico Schleiff, Weis, Benjamin L., Gisela Englich, Lucia E Groß, Schleiff, Enrico, Königer, Martina, Martina eKöniger, Bodo Tillmann, Groß, Lucia E., Sommer, Maik Sascha, Benjamin L. Weis, Bodo eTillmann, Martina Königer, Tillmann, Bodo, Maik S. Sommer   +23 more
core   +1 more source

Alignment of helical membrane protein sequences using AlignMe [PDF]

, 2013
Few sequence alignment methods have been designed specifically for integral membrane proteins, even though these important proteins have distinct evolutionary and structural properties that might affect their alignments.
René Staritzbichler, Stamm, Marcus, Staritzbichler, René, Khafizov, Kamil, Marcus Stamm (384964), Khafizov, K., Kamil Khafizov, Lucy R Forrest, René Staritzbichler (2667769), Staritzbichler, R., Marcus Stamm, Forrest, L., Forrest, Lucy R., Stamm, M., Kamil Khafizov (384965), Lucy R. Forrest (384966)   +15 more
core   +2 more sources

The use of SMALPs as a novel membrane protein scaffold for structure study by negative stain electron microscopy. [PDF]

, 2015
Despite the great progress recently made in resolving their structures, investigation of the structural biology of membrane proteins still presents major challenges.
Shaun Rawson, Mitchell, JK, Postis, Vincent; id_orcid, Vincent Postis, Tim R Dafforn, Postis, Vincent, Muench, Stephen P., Baldwin, SA, Rawson, Shaun, Baldwin, Stephen A., Postis, V, Rawson, S, Stephen A Baldwin, Lee, SC, Rosemary A Parslow, Mitchell, Jennifer K., Dafforn, TR, Lee, Sarah C., Parslow, Rosemary A., Jennifer K Mitchell, Sarah C Lee, Stephen P Muench, Muench, SP, Dafforn, Tim R., Parslow, RA   +24 more
core   +1 more source

Intercalated Cells: More than pH Regulation

Diseases, 2014
The renal collecting duct is the nephron segment where the final urine content of acid equivalents and inorganic ions are determined. The role of two different cell types present in this nephron segment has been determined many years ago: principal cells
Ensaf Y. Almomani, Sumanpreet Kaur, R. Todd Alexander, Emmanuelle Cordat   +3 more
doaj   +1 more source

The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter

Nature Communications, 2021
Vilazodone (VLZ) is a drug for the treatment of major depressive disorders that targets the serotonin transporter (SERT). Here, the authors combine pharmacology measurements and cryo-EM structural analysis to characterize VLZ binding to SERT and observe ...
Per Plenge, Dongxue Yang, Kristine Salomon, Louise Laursen, Iris E. Kalenderoglou, Amy H. Newman, Eric Gouaux, Jonathan A. Coleman, Claus J. Loland   +8 more
doaj   +1 more source

Analysis of leukocyte membrane protein interactions using protein microarrays [PDF]

, 2005
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work
Foster-Cuevas, M, Letarte, Michelle, Deborah Hatherley, Foster-Cuevas, Mildred, Hatherley, D, Barclay, AN, Michelle Letarte, Saunders, Nigel, A Neil Barclay, Saunders, NJ, Hatherley, Deborah, Letarte, M, Barclay, Neil, Mildred Foster-Cuevas, Nigel J Saunders, Saunders, Nigel J, Voulgaraki, D, Despina Voulgaraki, Voulgaraki, Despina   +18 more
core   +1 more source

Surfactant-free purification of membrane protein complexes from bacteria: application to the staphylococcal penicillin-binding protein complex PBP2/PBP2a. [PDF]

, 2014
Surfactant-mediated removal of proteins from biomembranes invariably results in partial or complete loss of function and disassembly of multi-protein complexes. We determined the capacity of styrene-co-maleic acid (SMA) co-polymer to remove components of
Taylor, Peter W, Paulin, S, Roper, David I, Garcia-Lara, J, Roper, DI, Taylor, PW, Galley, Nicola F., Paulin, Sarah, Rosado, H, Foster, SJ, Taylor, Peter W., Dafforn, TR, Dafforn, Tim, Dafforn, Timothy R, Galley, Nicola F, Jamshad, Mohammed, Rosado, Helena, Foster, Simon J, Garcia-Lara, Jorge, Jamshad, M, Galley, NF, Foster, Simon J., Roper, David I.   +22 more
core   +1 more source

Inward- and outward-facing homology modeling of human concentrative nucleoside transporter 3 (hCNT3) predicts an elevator-type transport mechanism

Channels, 2018
The human SLC28 family of concentrative (Na+-dependent) nucleoside transporters has three members, hCNT1, hCNT2 and hCNT3. Previously, we have used heterologous expression in Xenopus laevis oocytes in combination with an engineered cysteine-less hCNT3 ...
Sylvia Y. M. Yao, James D. Young
doaj   +1 more source

Electrophysiological characterization of a diverse group of sugar transporters from Trichoderma reesei

Scientific Reports, 2021
Trichoderma reesei is an ascomycete fungus known for its capability to secrete high amounts of extracellular cellulose- and hemicellulose-degrading enzymes. These enzymes are utilized in the production of second-generation biofuels and T.
Sami Havukainen, Jonai Pujol-Giménez, Mari Valkonen, Ann Westerholm-Parvinen, Matthias A. Hediger, Christopher P. Landowski   +5 more
doaj   +1 more source