Results 201 to 210 of about 2,329,860 (269)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Barrel expansion of outer membrane protein G nanopore through β-hairpin duplication. [PDF]

open access: yesProtein Sci
Foster JC   +9 more
europepmc   +1 more source

The integral membrane protein smim4 modulates redox balance via malate compartmentalization in pancreatic cancer. [PDF]

open access: yesNat Commun
Wang B   +18 more
europepmc   +1 more source

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