Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Rapid and Uniform NHS-Ester-Based Membrane Protein Labeling of Live Mammalian Cells. [PDF]
Burgess A, Gunasekara H, Hu YS.
europepmc +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
TurboID-based mapping of organelle membrane protein interactomes with digitonin-permeabilization. [PDF]
Sun Y +6 more
europepmc +1 more source
The Pheromone-Regulated Membrane Protein CsPRM10 Plays an Essential Role in the Asexual Reproduction of the Pepper Anthracnose Fungus <i>Colletotrichum scovillei</i>. [PDF]
Shen H +6 more
europepmc +1 more source
Barrel expansion of outer membrane protein G nanopore through β-hairpin duplication. [PDF]
Foster JC +9 more
europepmc +1 more source
The integral membrane protein smim4 modulates redox balance via malate compartmentalization in pancreatic cancer. [PDF]
Wang B +18 more
europepmc +1 more source
Identification of the client-binding site on the Golgi membrane protein adaptor Vps74/yGOLPH3. [PDF]
Lesniak AM, Ye Z, Banfield DK.
europepmc +1 more source

