Results 201 to 210 of about 2,393,838 (268)

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Outer membrane protein LipL21 as a potential candidate against Leptospira interrogans: An in silico prediction. [PDF]

Indian J Pharmacol
Kumari A, Toor D.
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Effects of Lipopolysaccharide Core Modulation on Outer Membrane Protein Function and Virulence in Pectobacterium carotovorum. [PDF]

Mol Plant Pathol
Park Y, Hwang J, Choi J, Goo E, Lee JH.
europepmc   +1 more source

Elucidation of the pramanicin biosynthetic pathway reveals a DUF2306 family membrane protein involved in terminal epoxidation. [PDF]

Front Microbiol
Gao YL, Chen W, Zhang JJ, Li PL, Li L, Zhang H.   +5 more
europepmc   +1 more source

Drop Dilution Enables the Use of PEG-Derived Detergents for Membrane Protein Purification. [PDF]

ACS Omega
Alker K, Singh S, Vinodakrishnan AK, Lindemann F, Linser R, Singh R, Singh AK, Urner LH.   +7 more
europepmc   +1 more source

The conserved outer mitochondrial membrane protein Mtch regulates mitophagy during Drosophila intestinal development. [PDF]

PLoS Biol
Restrepo LJ, Graslie JK, Fortier TM, Baehrecke EH.   +3 more
europepmc   +1 more source

A Computational Workflow for Membrane Protein-Ligand Interaction Studies: Focus on α5-Containing GABA (A) Receptors. [PDF]

Bio Protoc
Mohamad SMS, Halim KBA, Hamid AAA, Has ATC.   +3 more
europepmc   +1 more source

Chlamydial membrane vesicles deliver the beta barrel outer membrane protein OmpA to mitochondria to inhibit apoptosis. [PDF]

PLoS Pathog
Mesesan A, Oehler H, Kontchou CW, Haimovici A, Helmstädter M, Kretz O, Schilling O, Tholen S, Atanga J, Nazarenko I, Matti U, Ries J, Gentle IE, Häcker G.   +13 more
europepmc   +1 more source