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Structural and functional implications of phase separation of membrane protein LacY in Escherichia coli. [PDF]

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Linnik D   +8 more
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Proteomics of Membrane Proteins

2003
Publisher Summary The chapter focuses on the proteomics of the membrane proteins. As an increasing number of genomes are sequenced and a growing number of membrane proteins are identified, the gap in knowledge about the structure and function of these proteins is likely to increase. Moreover, in the post-genomic era, with proteomics emerging as a new
Julian P, Whitelegge   +2 more
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Membrane protein folding

Current Opinion in Structural Biology, 1999
Investigating the in vitro refolding of proteins that naturally reside in biological membranes is a notoriously difficult task. Biophysical studies on model systems are beginning to provide a sound physical basis for membrane protein folding that should help to alleviate this problem. Highlights of these studies include insights into the interaction of
P J, Booth, A R, Curran
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Microseparation of membrane proteins

Journal of Separation Science, 2009
AbstractMembrane proteins are generally of natural low abundance and insoluble to aqueous solutions. Thus, investigation of membrane proteins is relatively hampered since efficient separation of membrane proteins are rather challenging. Microseparation approaches certainly play an essential role in fulfilling such demanding investigations due to their ...
Zhaowei, Zhang   +4 more
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Membrane-protein topology

Nature Reviews Molecular Cell Biology, 2006
In the world of membrane proteins, topology defines an important halfway house between the amino-acid sequence and the fully folded three-dimensional structure. Although the concept of membrane-protein topology dates back at least 30 years, recent advances in the field of translocon-mediated membrane-protein assembly, proteome-wide studies of membrane ...
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