Results 281 to 290 of about 10,936,171 (356)

Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins. [PDF]

open access: yesScience
Jain A   +19 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Rab27a regulates the transport of influenza virus membrane proteins to the plasma membrane. [PDF]

open access: yesNat Commun
Chen T   +14 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

High-throughput peptide-centric local stability assay extends protein-ligand identification to membrane proteins, tissues and bacteria. [PDF]

open access: yesNat Struct Mol Biol
Li K   +7 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy