Results 151 to 160 of about 495,428 (314)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Remodeling of Granulocyte Membrane Fatty Acids During Phagocytosis [PDF]

, 1974
James E. Smolen, Stephen B. Shohet
openalex   +1 more source

Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome [PDF]

, 2021
A. Hempelmann, Laura Hartleb, Monique van Straaten, Hamidreza Hashemi, Johan Zeelen, Kevin Bongers, F. Nina Papavasiliou, Markus Engstler, C. Erec Stebbins, Nicola G. Jones   +9 more
openalex   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

SMN affects membrane remodelling and anchoring of the protein synthesis machinery [PDF]

, 2016
Francesca Gabanella, Cinzia Pisani, Antonella Borreca, Stefano Farioli‐Vecchioli, Ciotti Maria Teresa, Ingegnere Tiziano, Onori Annalisa, Martine Ammassari‐Teule, Nicoletta Corbi, Canu Nadia, Lucia Monaco, Claudio Passananti, Di Certo Maria Grazia   +12 more
openalex   +1 more source

Visualization of conformational changes and membrane remodeling leading to genome delivery by viral class-II fusion machinery [PDF]

, 2022
Vidya Mangala Prasad, Jelle S. Blijleven, Jolanda M. Smit, Kelly K. Lee   +3 more
openalex   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

The 6-kilodalton peptide 1 of the family Potyviridae: small in size but powerful in function

Frontiers in Microbiology
The Potyviridae family is one of the most economically significant groups of plant RNA viruses, causing severe yield losses in agriculturally important crops.
Liansheng Yu, Xayvangye Korxeelor, Ziyi Wang, Shuaifang Chang, Xue Jiang, Xiaoyun Wu, Xiaoyun Wu, Xiaofei Cheng   +7 more
doaj   +1 more source

Both GPER and membrane oestrogen receptor‐α activation protect ventricular remodelling in 17β oestradiol‐treated ovariectomized infarcted rats [PDF]

, 2014
Tsung‐Ming Lee, Shinn‐Zong Lin, Nen‐Chung Chang   +2 more
openalex   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source