Results 301 to 310 of about 495,428 (314)
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Organelle morphogenesis by active membrane remodeling
Soft Matter, 2015Eukaryotic cells are characterized by having well defined internal membrane bound organelles with distinct morphological identity. We explore the issue of morphogenesis in the context of organelles subject to intense membrane trafficking and show that non-equilibrium driven processes are at the heart of organelle morphogenesis.
Ramakrishnan, N. +3 more
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Membrane remodeling in clathrin-mediated endocytosis
Journal of Cell Science, 2018ABSTRACT Clathrin-mediated endocytosis is an essential cellular mechanism by which all eukaryotic cells regulate their plasma membrane composition to control processes ranging from cell signaling to adhesion, migration and morphogenesis. The formation of endocytic vesicles and tubules involves extensive protein-mediated remodeling of the
Volker Haucke, Michael M. Kozlov
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Membrane curvature and mechanisms of dynamic cell membrane remodelling
Nature, 2005Membrane curvature is no longer seen as a passive consequence of cellular activity but an active means to create membrane domains and to organize centres for membrane trafficking. Curvature can be dynamically modulated by changes in lipid composition, the oligomerization of curvature scaffolding proteins and the reversible insertion of protein regions ...
Harvey T, McMahon, Jennifer L, Gallop
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Membrane Remodelling During Reticulocyte Maturation
Physiology, 1989During maturation, reticulocytes lose many membrane functions, including the transferrin receptor. Immunocytochemical studies reveal that after endocytosis the transferrin receptor (and many other membrane proteins) is packaged into multivesicular bodies. The vesicular contents are externalized by exocytosis.
RM Johnstone, K Teng
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Visualizing BAR-Dependent Membrane Remodeling
Microscopy and Microanalysis, 2012Extended abstract of a paper presented at Microscopy and Microanalysis 2012 in Phoenix, Arizona, USA, July 29 – August 2, 2012.
C. Mim +3 more
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Membrane Remodeling Processes Induced by Phospholipase Action
Langmuir, 2014Important cellular events such as division require drastic changes in the shape of the membrane. These remodeling processes can be triggered by the binding of specific proteins or by changes in membrane composition and are linked to phospholipid metabolism for which dedicated enzymes, named phospholipases, are responsible.
Rocha, Susana +6 more
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Remodeling Mitochondrial Membranes during Arousal from Hibernation
Physiological and Biochemical Zoology, 2011During arousal from hibernation, body temperature (T(b)) increases by ∼30°C and liver mitochondrial respiration increases threefold in as little as 2 h. We analyzed liver mitochondria purified from ground squirrels (Ictidomys tridecemlineatus) to see whether membrane phospholipids were remodeled during spontaneous arousal.
Christopher, Armstrong +4 more
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Synthetic cell membranes remodeled chemically
C&EN Global Enterprise, 2016Researchers have developed a way to chemically remodel synthetic cell membranes, similar to the way enzymes remodel mammalian cell membranes in living cells. In biological cells, the remodeling of membrane phospholipids by enzymes such as acyltransferases and transacylases plays a key role in many cell functions, such as division, membrane transport ...
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Dynamic Remodeling of Membranes Catalyzed by Dynamin
2011Publisher Summary This chapter discusses the dynamic remodeling of membranes catalyzed by dynamin. Members of the dynamin family of large GTPases are unique among proteins involved in remodeling cell membranes. They readily polymerize on favorable membrane templates and display reversible modes of membrane association that is coupled to their GTPase ...
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