Results 71 to 80 of about 2,449,697 (312)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
, 2014 The membrane fouling and filtration performance of Bovine serum albumin (BSA)/dextran cross-flow microfiltration using membranes with different morphologies are analyzed and compared. Three 0.1 μm hydrophilic membranes made of mixed cellulose ester (MCE),
Hwang, Kuo-Jen +1 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Hydrogen separation/purification via membrane technology
, 2020 Special issue of the International Journal of Hydrogen Energy on "Hydrogen separation/purification via membrane ...
Iulianelli A, Basile A
core
Engineering evaluation of CO2 separation by membrane gas separation systems
, 2014 The possible application of membranes for CO2 separation in the treatment of non-valuable streams (e.g.,flue gas of a power plant or cement industry) or valuable streams (e.g., biogas) has been analyzed.
Lee YM +4 more
core +1 more source
, 2021 High-efficient CO2 capture using membrane separation technology is a promising approach towards environmental redemption in recent years. Thin-film composite (TFC) membrane with selective layer made of CO2-philic materials is the preferred membrane type ...
Goh, Kunli +3 more
core +1 more source