Results 21 to 30 of about 9,333,423 (166)

A Brief Introduction to Some Aspects of the Fluid–Mosaic Model of Cell Membrane Structure and Its Importance in Membrane Lipid Replacement

Membranes, 2021
Early cell membrane models placed most proteins external to lipid bilayers in trimolecular structures or as modular lipoprotein units. These thermodynamically untenable structures did not allow lipid lateral movements independent of membrane proteins ...
Garth L. Nicolson, Gonzalo Ferreira de Mattos   +1 more
doaj   +1 more source

Membrane fouling in osmotically driven membrane processes: A review

, 2016
The utilization of osmosis for engineered applications sparked off various emerging technologies relying on osmotically driven membrane processes (ODMPs).
Fane, Anthony Gordon, Tang, C, She, Q, Wang, Rong, She, Qianhong, Tang, Chuyang Y., Wang, R, Fane, AG   +7 more
core   +1 more source

Routing of the RAB6 secretory pathway towards the lysosome related organelle of melanocytes

Nature Communications, 2017
The anterograde movement of Golgi-derived vesicles requires the small GTPase RAB6, while its effector ELKS targets these vesicles to particular areas of the plasma membrane.
Anand Patwardhan, Sabine Bardin, Stéphanie Miserey-Lenkei, Lionel Larue, Bruno Goud, Graça Raposo, Cédric Delevoye   +6 more
doaj   +1 more source

Solubilization of lipids and membrane proteins into nanodiscs: Mode of action and applications of SMA copolymers [PDF]

, 2016
Cell membranes separate the inside and outside of cells. Membrane proteins in the cell membrane control the traffic of molecules across the membrane and are therefore targets for a lot of drugs: about 50 % of all approved drugs target a membrane protein!
Scheidelaar, S., Sub Membrane Biochemistry & Biophysics, Membrane Biochemistry and Biophysics   +2 more
core  

Influence of membrane structure-dependent water transport on conductivity-permselectivity trade-off and salt/water selectivity in electrodialysis: implications for osmotic electrodialysis using porous ion exchange membranes

, 2022
Water transport, including osmosis and electroosmosis, is an important phenomenon in electrodialysis (ED) but is generally ignored in many studies on the analysis of ion transport. Having a fundamental understanding of the influence of water transport on
She, Qianhong, Liu, Hong
core   +1 more source

A trimeric architecture reveals the glucitol PTS transporter as a distinct superfamily

Communications Biology
The bacterial phosphoenolpyruvate:sugar phosphotransferase system (PTS) catalyzes the transport and phosphorylation of carbohydrates. The glucitol (Gut) PTS transporter from Escherichia coli has often been discussed in relation to the Glucose–Fructose ...
Tingyue Deng, Xueli Liu, Jianwei Zeng, Xiaofei Ge, Jiawei Wang   +4 more
doaj   +1 more source

Molecular mechanism of PINK1 regulation by the Hsp90 machinery

Nature Communications
Hundreds of human kinases, including PINK1—a protein kinase associated with familial Parkinson’s disease—are regulated by Hsp90 and its cochaperones. While previous studies have elucidated the mechanism of kinase loading into the Hsp90 machinery, the ...
Xuyang Tian, Jiayue Su, Ziyi Wang, Tao Liu, Huifang Xiong, Shan Sun, Kunrong Mei, Sen-Fang Sui   +7 more
doaj   +1 more source

Structural basis for the extended-spectrum antimicrobial activity of Garvieacin Q

Applied and Environmental Microbiology
Class IIa and IId bacteriocins are antimicrobial peptides with potential for combating antibiotic-resistant pathogens. However, their species-specific activity, dictated by recognition of the mannose phosphotransferase system (Man-PTS) receptor, often ...
Jinsong Duan, Dan Li, Yuqing Zhao, Jiawei Wang   +3 more
doaj   +1 more source

Effect of humic-acid fouling on membrane distillation

, 2016
Membrane distillation (MD) can concentrate non-volatile solutes or remove volatiles and dissolved gases from an aqueous feed. A microporous hydrophobic membrane provides a barrier between the hot feed and cold distillate.
Tan, Yong Zen, Krantz, William B., Chew, Jia Wei   +2 more
core   +1 more source

Cas12e orthologs evolve variable structural elements to facilitate dsDNA cleavage

Nature Communications
Exceptionally diverse type V CRISPR-Cas systems provide numerous RNA-guided nucleases as powerful tools for DNA manipulation. Two known Cas12e nucleases, DpbCas12e and PlmCas12e, are both effective in genome editing.
Danyuan Li, Shouyue Zhang, Shuo Lin, Wenjing Xing, Yun Yang, Fengxia Zhu, Dingding Su, Chunlai Chen, Jun-Jie Gogo Liu   +8 more
doaj   +1 more source