Results 191 to 200 of about 1,504,627 (332)

Membrane Transporters & Exchangers [PDF]

Biophysical Journal, 2008
openaire   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

The PKD-Dependent Biogenesis of TGN-to-Plasma Membrane Transport Carriers. [PDF]

Cells, 2021
Wakana Y, Campelo F.
europepmc   +1 more source

Sucrose transport across the vacuolar membrane of Ananas comosus

, 2002
Shelley R. McRae, Jack Christopher, J. Andrew C. Smith, Joseph A. M. Holtum   +3 more
openalex   +1 more source

Structural basis for mitoguardin-2 mediated lipid transport at ER-mitochondrial membrane contact sites

, 2022
Hyunwoo Kim, Seowhang Lee, Youngsoo Jun, Changwook Lee   +3 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Passive Membrane Transport Analysis of Drug Mixtures. [PDF]

Anal Chem
Strutt R, Berlanda SF, Dittrich PS.
europepmc   +1 more source

Geraniol as a Potential Stimulant for Improving Anthocyanin Accumulation in Grape Berry Skin through ABA Membrane Transport. [PDF]

Plants (Basel), 2022
Mikami N, Konya M, Enoki S, Suzuki S.
europepmc   +1 more source

Cell-Penetrating Peptide for Transcellular Transport: Membrane Binding and Uptake in Live Cells [PDF]

, 2017
Alexander Komin, Michael Paul, Alexander M. Luera, Peter C. Searson, Kalina Hristova   +4 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source