Results 181 to 190 of about 4,164,744 (312)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Wuji Wan ameliorates ulcerative colitis by restoring impaired membrane transport. [PDF]

Front Pharmacol
Zhang J, Zhang Y, Guo Y, Sun Y, Li Y, Li Q, Chen Y, Wang Y, Yang Q, Zhang M, Weng X, Deng Z.   +11 more
europepmc   +1 more source

Reconstitution of a minimal ESX-5 type VII secretion system suggests a role for PPE proteins in the outer membrane transport of proteins. [PDF]

mSphere, 2023
Bunduc CM, Ding Y, Kuijl C, Marlovits TC, Bitter W, Houben ENG.   +5 more
europepmc   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Deletion of <i>FgSRE1</i> Impairs Reproduction and Virulence of <i>Fusarium graminearum</i> and Alters Metabolic and Membrane-Transport Gene Expression. [PDF]

J Fungi (Basel)
Shen L, Hui H, Guo L, Wang J, Cui J, Xu H, He X, Huang Y, Liu B.   +8 more
europepmc   +1 more source

Magnetic-controlled membrane transport. [PDF]

Natl Sci Rev, 2021
Lammertink RGH.
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Passive Membrane Transport Analysis of Drug Mixtures. [PDF]

Anal Chem
Strutt R, Berlanda SF, Dittrich PS.
europepmc   +1 more source

Essential phospholipids decrease apoptosis and increase membrane transport in human hepatocyte cell lines. [PDF]

Lipids Health Dis, 2022
Wupperfeld D, Fricker G, Bois De Fer B, Frank L, Wehrle A, Popovic B.   +5 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source