Results 181 to 190 of about 917,628 (315)

Passive Membrane Transport Analysis of Drug Mixtures. [PDF]

Anal Chem
Strutt R, Berlanda SF, Dittrich PS.
europepmc   +1 more source

Stereoselectivity in the Membrane Transport of Phenylethylamine Derivatives by Human Monoamine Transporters and Organic Cation Transporters 1, 2, and 3. [PDF]

Biomolecules, 2022
Gebauer L, Rafehi M, Brockmöller J.
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Membrane transport of root-borne trans-zeatin riboside maintains the cytokinin homeostasis in shoots. [PDF]

J Exp Bot
Nedvěd D, Hudeček M, Klíma P, Lacek J, Müller K, Kuchařová A, Hošek P, Šmeringai J, Pernisová M, Motyka V, Plíhal O, Hoyerová K.   +11 more
europepmc   +1 more source

Membrane Transport Proteins in Osteoclasts: The Ins and Outs. [PDF]

Front Cell Dev Biol, 2021
Ribet ABP, Ng PY, Pavlos NJ.
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

The SLC-ome of membrane transport: From molecular discovery to physiology and clinical applications. [PDF]

Physiol Rev
Gyimesi G, Tweedie S, Bruford E, Hediger MA.   +3 more
europepmc   +1 more source

The PKD-Dependent Biogenesis of TGN-to-Plasma Membrane Transport Carriers. [PDF]

Cells, 2021
Wakana Y, Campelo F.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The role of GRASP65 and GRASP55 in C-terminal valine-dependent transport to the cell surface of transmembrane proteins

, 2008
The Golgi-matrix proteins GRASP65 and GRASP55 have recognized roles in maintaining the architecture of the Golgi complex, in mitotic progression and in unconventional protein secretion while, surprisingly, they have been shown to be dispensable for the ...
Prencipe, Libera
core