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Therapeutic Nanobodies Targeting Cell Plasma Membrane Transport Proteins: A High-Risk/High-Gain Endeavor [PDF]
Biomolecules, 2021 Cell plasma membrane proteins are considered as gatekeepers of the cell and play a major role in regulating various processes. Transport proteins constitute a subclass of cell plasma membrane proteins enabling the exchange of molecules and ions between ...
Raf Van Campenhout +4 more
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Transport of Ciliary Membrane Proteins [PDF]
Frontiers in Cell and Developmental Biology, 2020 Cilia and flagella are highly conserved organelles in eukaryotic cells that drive cell movement and act as cell antennae that receive and transmit signals.
Huan Long, Kaiyao Huang
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Membrane Transport Proteins in Osteoclasts: The Ins and Outs [PDF]
Frontiers in Cell and Developmental Biology, 2021 During bone resorption, the osteoclast must sustain an extraordinarily low pH environment, withstand immense ionic pressures, and coordinate nutrient and waste exchange across its membrane to sustain its unique structural and functional polarity.
Amy B. P. Ribet +2 more
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Mechanism Study of Proteins under Membrane Environment
Membranes, 2022 Membrane proteins play crucial roles in various physiological processes, including molecule transport across membranes, cell communication, and signal transduction. Approximately 60% of known drug targets are membrane proteins.
Yue Zhang +7 more
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Genes for Membrane Transport Proteins: Not So Rare in Viruses [PDF]
Viruses, 2018 Some viruses have genes encoding proteins with membrane transport functions. It is unknown if these types of proteins are rare or are common in viruses.
Timo Greiner +3 more
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The Road not Taken: Less Traveled Roads from the TGN to the Plasma Membrane [PDF]
Membranes, 2015 The trans-Golgi network functions in the distribution of cargo into different transport vesicles that are destined to endosomes, lysosomes and the plasma membrane.
Anne Spang
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Updating view of membrane transport proteins by simulation studies [PDF]
Biophysics and Physicobiology, 2023 Takashi Sumikama +4 more
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Analysis of outer membrane vesicle associated proteins isolated from the plant pathogenic bacterium
BMC Microbiology, 2008 Background Outer membrane vesicles (OMVs) are released from the outer membrane of many Gram-negative bacteria. These extracellular compartments are known to transport compounds involved in cell-cell signalling as well as virulence associated proteins, e ...
Niehaus Karsten +3 more
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Single-Molecule FRET of Membrane Transport Proteins. [PDF]
Chembiochem, 2021 AbstractUncovering the structure and function of biomolecules is a fundamental goal in structural biology. Membrane‐embedded transport proteins are ubiquitous in all kingdoms of life. Despite structural flexibility, their mechanisms are typically studied by ensemble biochemical methods or by static high‐resolution structures, which complicate a ...
Bartels K +3 more
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Computational and Structural Biotechnology Journal, 2023 Potassium is an essential intracellular ion, and a sufficient intracellular concentration of it is crucial for many processes; therefore it is fundamental for cells to precisely regulate K+ uptake and efflux through the plasma membrane.
Jakub Masaryk +7 more
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