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Therapeutic Nanobodies Targeting Cell Plasma Membrane Transport Proteins: A High-Risk/High-Gain Endeavor [PDF]
Cell plasma membrane proteins are considered as gatekeepers of the cell and play a major role in regulating various processes. Transport proteins constitute a subclass of cell plasma membrane proteins enabling the exchange of molecules and ions between ...
Raf Van Campenhout +4 more
doaj +4 more sources
Single-Molecule FRET of Membrane Transport Proteins. [PDF]
AbstractUncovering the structure and function of biomolecules is a fundamental goal in structural biology. Membrane‐embedded transport proteins are ubiquitous in all kingdoms of life. Despite structural flexibility, their mechanisms are typically studied by ensemble biochemical methods or by static high‐resolution structures, which complicate a ...
Bartels K +3 more
europepmc +6 more sources
Transport of Ciliary Membrane Proteins [PDF]
Cilia and flagella are highly conserved organelles in eukaryotic cells that drive cell movement and act as cell antennae that receive and transmit signals.
Huan Long, Kaiyao Huang
doaj +3 more sources
Membrane Transport Proteins in Osteoclasts: The Ins and Outs [PDF]
During bone resorption, the osteoclast must sustain an extraordinarily low pH environment, withstand immense ionic pressures, and coordinate nutrient and waste exchange across its membrane to sustain its unique structural and functional polarity.
Amy B. P. Ribet +2 more
doaj +2 more sources
Genes for Membrane Transport Proteins: Not So Rare in Viruses [PDF]
Some viruses have genes encoding proteins with membrane transport functions. It is unknown if these types of proteins are rare or are common in viruses.
Timo Greiner +3 more
doaj +2 more sources
Activity assay of membrane transport proteins [PDF]
Membrane transport proteins are integral membrane proteins and considered as potential drug targets. Activity assay of transport proteins is essential for developing drugs to target these proteins. Major issues related to activity assessment of transport proteins include availability of transporters, transport activity of transporters, and interactions
Hao Xie
exaly +3 more sources
Updating view of membrane transport proteins by simulation studies [PDF]
Takashi Sumikama +4 more
doaj +2 more sources
Microbial membrane transport proteins and their biotechnological applications. [PDF]
Özkan M +4 more
europepmc +2 more sources
Potassium is an essential intracellular ion, and a sufficient intracellular concentration of it is crucial for many processes; therefore it is fundamental for cells to precisely regulate K+ uptake and efflux through the plasma membrane.
Jakub Masaryk +7 more
doaj +1 more source
Peroxisomal Metabolite and Cofactor Transport in Humans
Peroxisomes are membrane-bound organelles involved in many metabolic pathways and essential for human health. They harbor a large number of enzymes involved in the different pathways, thus requiring transport of substrates, products and cofactors ...
Serhii Chornyi +4 more
doaj +1 more source

