Results 41 to 50 of about 5,038,071 (294)

Evolution of the Membrane Transport Protein Domain

International Journal of Molecular Sciences, 2022
Membrane transport proteins are widely present in all living organisms, however, their function, transported substrate, and mechanism of action are unknown. Here we use diverse bioinformatics tools to investigate the evolution of MTPs, analyse domain organisation and loop topology, and study the comparative alignment of modelled 3D structures.
Siarhei A. Dabravolski, Stanislav V. Isayenkov   +1 more
openaire   +2 more sources

CDC50 proteins are critical components of the human class-1 P 4-ATPase transport machinery [PDF]

, 2010
Members of the P4 subfamily of P-type ATPases catalyze phospholipid transport and create membrane lipid asymmetry in late secretory and endocytic compartments.
Patricia M. Verhulst, Guillaume Lenoir, Hennrich, H., Lenoir, G.F., Devaux, P.F., Verhulst, P.M., Philippe F. Devaux, Susanne Bryde, Sub Membrane Enzymology begr. 01-06-12, Hanka Hennrich, Joost C.M. Holthuis, Holthuis, J.C.M., Bryde, S., Dep Scheikunde, Membrane Enzymology   +14 more
core   +2 more sources

Cation permeability in CorA family of proteins

Scientific Reports, 2020
CorA proteins belong to 2-TM-GxN family of membrane proteins, and play a major role in Mg2+ transport in prokaryotes and eukaryotic mitochondria. The selection of substrate is believed to occur via the signature motif GxN, however there is no consensus ...
Artem Stetsenko, Albert Guskov
doaj   +1 more source

Legionella pneumophila secretes a mitochondrial carrier protein during infection.

PLoS Pathogens, 2012
The Mitochondrial Carrier Family (MCF) is a signature group of integral membrane proteins that transport metabolites across the mitochondrial inner membrane in eukaryotes. MCF proteins are characterized by six transmembrane segments that assemble to form
Pavel Dolezal, Margareta Aili, Janette Tong, Jhih-Hang Jiang, Carlo M T Marobbio, Sau Fung Lee, Ralf Schuelein, Simon Belluzzo, Eva Binova, Aurelie Mousnier, Gad Frankel, Giulia Giannuzzi, Ferdinando Palmieri, Kipros Gabriel, Thomas Naderer, Elizabeth L Hartland, Trevor Lithgow   +16 more
doaj   +1 more source

ORP1L, ORP1S, and ORP2: Lipid Sensors and Transporters

Contact, 2020
Lipid transfer proteins are crucial for intracellular cholesterol trafficking at sites of membrane contact. In the OSBP/ORPs (oxysterol binding protein and OSBP-related proteins) family of lipid transfer proteins, ORP1L, ORP1S and ORP2 play important ...
Yvette C. Aw, Andrew J. Brown, Jia-Wei Wu, Hongyuan Yang   +3 more
doaj   +1 more source

Characterization of Translocation Contact Sites Involved in the Import of Mitochondrial Proteins [PDF]

, 1987
Import of proteins into the mitochondrial matrix requires translocation across two membranes. Translocational intermediates of mitochondrial proteins, which span the outer and inner membrane simultaneously and thus suggest that translocation occurs in ...
Herzog, Volker, W Neupert, Schwaiger, Martin, M Schwaiger, Neupert, Walter, V Herzog   +5 more
core   +2 more sources

Membrane glycine transport proteins

Journal of Biomedical Science, 2003
Structurally, the simplest amino acid is glycine, and it has a number of important yet distinct functions in the body. This review focuses on the different transport systems and the associated carrier proteins for glycine that are responsible for its movement across biological membranes.
openaire   +2 more sources

Membrane transport proteins of the malaria parasite [PDF]

Molecular Microbiology, 2009
SummaryThe malaria parasite‐infected erythrocyte is a multi‐compartment structure, incorporating numerous different membrane systems. The movement of nutrients, metabolites and inorganic ions into and out of the intraerythrocytic parasite, as well as between subcellular compartments within the parasite, is mediated by transporters and channels ...
Martin, Rowena, Ginsburg, Hagai, Kirk, Kiaran   +2 more
openaire   +3 more sources

Multiple novel membrane proteins involve phthalate ester degradation in Rhodococcus sp. AH-ZY2

Applied and Environmental Microbiology
Phthalate esters (PAEs) are ubiquitous in the environment, and their microbial metabolism is associated with transport proteins. In this study, multiple novel membrane proteins were identified, revealing their pivotal role in PAEs degradation.
Zhengyu Hou, Hejuan Pan, Shihan Wang, Yulin Li, Yang Yu, Pei Qiao, Haixia Wang, Weihong Zhong   +7 more
doaj   +1 more source

Structural and functional studies of bacterial outer membrane proteins [PDF]

, 2010
This thesis studies two particular bacterial outer membrane proteins called OmpC and Wzi, focusing on their expression, purification, crystallization and X-ray structure determination.
Lou, Hubing
core   +2 more sources