Results 41 to 50 of about 5,306,314 (299)

Plasma membrane compartmentation in Saccharomyces cerevisiae [PDF]

open access: yes, 2009
In the plasma membrane of cells the complex variety of components is sorted into subcompartments, microdomains and nanoclusters. We only begin to understand the principles of this higher order.
Großmann, Guido
core   +1 more source

Evolution of the Membrane Transport Protein Domain

open access: yesInternational Journal of Molecular Sciences, 2022
Membrane transport proteins are widely present in all living organisms, however, their function, transported substrate, and mechanism of action are unknown. Here we use diverse bioinformatics tools to investigate the evolution of MTPs, analyse domain organisation and loop topology, and study the comparative alignment of modelled 3D structures.
Siarhei A. Dabravolski   +1 more
openaire   +2 more sources

Cation permeability in CorA family of proteins

open access: yesScientific Reports, 2020
CorA proteins belong to 2-TM-GxN family of membrane proteins, and play a major role in Mg2+ transport in prokaryotes and eukaryotic mitochondria. The selection of substrate is believed to occur via the signature motif GxN, however there is no consensus ...
Artem Stetsenko, Albert Guskov
doaj   +1 more source

Glycosylation can influence topogenesis of membrane proteins and reveals dynamic reorientation of nascent polypeptides within the translocon [PDF]

open access: yes, 1999
The topology of multispanning membrane proteins in the mammalian endoplasmic reticulum is thought to be dictated primarily by the first hydrophobic sequence.
Martin Spiess   +8 more
core   +1 more source

The role of GRASP65 and GRASP55 in C-terminal valine-dependent transport to the cell surface of transmembrane proteins [PDF]

open access: yes, 2008
The Golgi-matrix proteins GRASP65 and GRASP55 have recognized roles in maintaining the architecture of the Golgi complex, in mitotic progression and in unconventional protein secretion while, surprisingly, they have been shown to be dispensable for the ...
Prencipe, Libera
core   +1 more source

Legionella pneumophila secretes a mitochondrial carrier protein during infection.

open access: yesPLoS Pathogens, 2012
The Mitochondrial Carrier Family (MCF) is a signature group of integral membrane proteins that transport metabolites across the mitochondrial inner membrane in eukaryotes. MCF proteins are characterized by six transmembrane segments that assemble to form
Pavel Dolezal   +16 more
doaj   +1 more source

ORP1L, ORP1S, and ORP2: Lipid Sensors and Transporters

open access: yesContact, 2020
Lipid transfer proteins are crucial for intracellular cholesterol trafficking at sites of membrane contact. In the OSBP/ORPs (oxysterol binding protein and OSBP-related proteins) family of lipid transfer proteins, ORP1L, ORP1S and ORP2 play important ...
Yvette C. Aw   +3 more
doaj   +1 more source

Membrane glycine transport proteins

open access: yesJournal of Biomedical Science, 2003
Structurally, the simplest amino acid is glycine, and it has a number of important yet distinct functions in the body. This review focuses on the different transport systems and the associated carrier proteins for glycine that are responsible for its movement across biological membranes.
openaire   +2 more sources

Membrane transport proteins of the malaria parasite [PDF]

open access: yesMolecular Microbiology, 2009
SummaryThe malaria parasite‐infected erythrocyte is a multi‐compartment structure, incorporating numerous different membrane systems. The movement of nutrients, metabolites and inorganic ions into and out of the intraerythrocytic parasite, as well as between subcellular compartments within the parasite, is mediated by transporters and channels ...
Martin, Rowena   +2 more
openaire   +3 more sources

ATP2, The essential P4-ATPase of malaria parasites, catalyzes lipid-stimulated ATP hydrolysis in complex with a Cdc50 β-subunit

open access: yesEmerging Microbes and Infections, 2021
Gene targeting approaches have demonstrated the essential role for the malaria parasite of membrane transport proteins involved in lipid transport and in the maintenance of membrane lipid asymmetry, representing emerging oportunites for therapeutical ...
Anaïs Lamy   +7 more
doaj   +1 more source

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