Results 61 to 70 of about 5,038,071 (294)

The EXO70 inhibitor Endosidin2 alters plasma membrane protein composition in Arabidopsis roots

Frontiers in Plant Science, 2023
To sustain normal growth and allow rapid responses to environmental cues, plants alter the plasma membrane protein composition under different conditions presumably by regulation of delivery, stability, and internalization.
Xiaohui Li, Xiaohui Li, Peipei Zhu, Peipei Zhu, Yen-Ju Chen, Yen-Ju Chen, Lei Huang, Lei Huang, Diwen Wang, Diwen Wang, David T. Newton, Chuan-Chih Hsu, Guang Lin, Guang Lin, W. Andy Tao, W. Andy Tao, Christopher J. Staiger, Christopher J. Staiger, Christopher J. Staiger, Chunhua Zhang, Chunhua Zhang   +20 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Import pathways of precursor proteins into mitochondria [PDF]

, 1988
The precursor of porin, a mitochondrial outer membrane protein, competes for the import of precursors destined for the three other mitochondrial compartments, including the Fe/S protein of the bc1- complex (intermembrane space), the ADP/ATP carrier ...
Pfaller, Rupert, Pfanner, Nikolaus, Steger, Heinrich F., Rassow, Joachim, Neupert, Walter   +4 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Membrane proteins in the outer mebrane of plastids and mitochondria [PDF]

, 2006
Channels of the plastid and mitochondrial outer membranes facilitate the turnover of molecules and ions via these membranes. Although channels have been studied many questions pertaining to the whole diversity of plastid and mitochondrial channels in ...
Ilkavets, Iryna
core   +1 more source

Towards Atomic Force Microscopy and Mass Spectrometry to visualize and identify lipid rafts in Plasmodesmata

Frontiers in Plant Science, 2014
Plant cell-to-cell communication is mediated by nanopores called plasmodesmata (PDs) which are complex structures comprising plasma membrane (PM), highly packed endoplasmic reticulum and numerous membrane proteins.
Pamela Alejandra Naulin, Natalia eAlveal, Nelson Patricio Barrera   +2 more
doaj   +1 more source

A cytosolic factor mediating membrane recruitment of AP-1 clathrin adaptors [PDF]

, 2008
Transport of cargo within the endocytic and secretory pathway is generally mediated by coated vesicles. These vesicles are formed through the recruitment of cytosolic coat proteins to the donor membrane that act as a scaffold to form coated buds and ...
Suri, Gregor
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Membrane and luminal proteins reach the apicoplast by different trafficking pathways in the malaria parasite Plasmodium falciparum [PDF]

PeerJ, 2017
The secretory pathway in Plasmodium falciparum has evolved to transport proteins to the host cell membrane and to an endosymbiotic organelle, the apicoplast. The latter can occur via the ER or the ER-Golgi route.
Rahul Chaudhari, Vishakha Dey, Aishwarya Narayan, Shobhona Sharma, Swati Patankar   +4 more
doaj   +2 more sources